Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 5/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.36 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8531514 | 0.91 | FOLH1 (0.41) | FOLH1LMNATDP1HSD17B10ALDH1A1 | |
| SCHEMBL15757375 | 0.85 | LMNA (0.49) | LMNATDP1HSD17B10ALDH1A1TSHR | |
| SCHEMBL343431 | 0.80 | TSHR (0.32) | ALDH1A1TSHRFAAH | |
| SCHEMBL5231959 | 0.77 | LMNA (0.44) | LMNATDP1HSD17B10ALDH1A1TSHR | |
| SCHEMBL3047626 | 0.76 | FAAH (0.37) | TSHRFAAH | |
| SCHEMBL8400937 | 0.76 | LMNA (0.52) | FOLH1LMNATDP1HSD17B10ALDH1A1 | |
| SCHEMBL7939245 | 0.67 | — | — | |
| SCHEMBL1695048 | 0.67 | CYP2D6 (0.40) | FAAH | |
| SCHEMBL24003308 | 0.66 | LMNA (0.59) | FOLH1LMNATDP1HSD17B10ALDH1A1 | |
| SCHEMBL7428860 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007053869-A2 | NOVEL 2,2-DITHIOSUBSTITUTED FURANOSE DERIVATIVES, METHOD FOR THE PRODUCTION AND USE THEREOF | SAISCHEK UND PARTNER MEG (AT) | 2007-05-18 | — | — | WO | disclosed |