Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | MYC | P01106 | 1/20 | 0.42 |
| ▸ | WDR5 | P61964 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | USP8 | P40818 | 1/20 | 0.38 |
| ▸ | USP7 | Q93009 | 1/20 | 0.38 |
| ▸ | USP47 | Q96K76 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8400494 | 0.77 | MYC (0.40) | KDM4EALDH1A1HSD17B10MYCWDR5 | |
| SCHEMBL8792142 | 0.76 | MYC (0.52) | KDM4EALDH1A1MYCWDR5HPGD | |
| SCHEMBL8401142 | 0.73 | SMN1; SMN2 (0.41) | KDM4EALDH1A1HSD17B10MYCWDR5 | |
| SCHEMBL31438207 | 0.72 | ERBB2 (0.59) | KDM4EALDH1A1HSD17B10MYCWDR5 | |
| SCHEMBL8792488 | 0.70 | MYC (0.41) | KDM4EALDH1A1HSD17B10MYCWDR5 | |
| SCHEMBL8400161 | 0.69 | DPP4 (0.38) | KDM4EALDH1A1HSD17B10MYCWDR5 | |
| SCHEMBL23921774 | 0.69 | KDM4E (0.50) | KDM4EALDH1A1HSD17B10MYCWDR5 | |
| SCHEMBL8400434 | 0.68 | RAB9A (0.50) | KDM4EALDH1A1HSD17B10HPGDNPC1 | |
| SCHEMBL6208520 | 0.68 | MYC (0.41) | KDM4EALDH1A1HSD17B10MYCWDR5 | |
| SCHEMBL7685812 | 0.68 | NPC1 (0.42) | KDM4EALDH1A1HSD17B10MYCWDR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5948916-A | Arylthiadiazole derivative and antiviral agent containing the same | RATIONAL DRUG DESIGN LABORATORIES (JP) | 1999-09-07 | — | — | US | disclosed |
| EP-0785193-A1 | ARYLTHIADIAZOLE DERIVATIVE AND ANTIVIRAL AGENT CONTAINING THE SAME | Rational Drug Design Laboratories (JP) | 1997-07-23 | — | — | EP | disclosed |