Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | LDHA | P00338 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | DCUN1D1 | Q96GG9 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8400494 | 0.80 | MYC (0.40) | DPP4ALDH1A1TDP1L3MBTL1CYP2A6 | |
| SCHEMBL8396823 | 0.78 | RXFP1 (0.49) | DPP4ALDH1A1TP53KDM4EKMT2A | |
| SCHEMBL8401142 | 0.77 | SMN1; SMN2 (0.41) | DPP4ALDH1A1TDP1L3MBTL1CYP2A6 | |
| SCHEMBL1599020 | 0.71 | KDM4E (0.44) | DPP4ALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL1598248 | 0.71 | KDM4E (0.41) | DPP4ALDH1A1SMN1; SMN2HPGDNPC1 | |
| SCHEMBL8401140 | 0.69 | KDM4E (0.42) | ALDH1A1L3MBTL1SMN1; SMN2HPGDNPC1 | |
| SCHEMBL8400434 | 0.68 | RAB9A (0.50) | ALDH1A1TDP1CYP2A6SMN1; SMN2HPGD | |
| SCHEMBL1598282 | 0.67 | MAPT (0.48) | RAB9AKMT2A | |
| SCHEMBL1598249 | 0.67 | PIK3CD (0.49) | ALDH1A1NPC1RAB9AKDM4EGLA | |
| SCHEMBL1598069 | 0.67 | ALDH1A1 (0.40) | ALDH1A1L3MBTL1SMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5948916-A | Arylthiadiazole derivative and antiviral agent containing the same | RATIONAL DRUG DESIGN LABORATORIES (JP) | 1999-09-07 | — | — | US | disclosed |
| EP-0785193-A1 | ARYLTHIADIAZOLE DERIVATIVE AND ANTIVIRAL AGENT CONTAINING THE SAME | Rational Drug Design Laboratories (JP) | 1997-07-23 | — | — | EP | disclosed |