Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 14/20 | 0.60 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | PPIA | P62937 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8404952 | 0.92 | ELANE (0.52) | ELANECYP19A1NPC1RAB9A | |
| SCHEMBL27451145 | 0.90 | ELANE (0.55) | ELANENPC1RAB9A | |
| SCHEMBL27467025 | 0.89 | ELANE (0.51) | ELANENPC1RAB9A | |
| SCHEMBL8401403 | 0.87 | ELANE (0.58) | ELANENPC1RAB9A | |
| SCHEMBL8401430 | 0.87 | ELANE (0.59) | ELANENPC1RAB9A | |
| SCHEMBL8401199 | 0.86 | ELANE (0.59) | ELANENPC1RAB9A | |
| SCHEMBL8401406 | 0.86 | ELANE (0.50) | ELANENPC1RAB9A | |
| SCHEMBL6558186 | 0.84 | ELANE (0.71) | ELANE | |
| SCHEMBL8405263 | 0.83 | ELANE (0.58) | ELANENPC1RAB9A | |
| SCHEMBL6556126 | 0.82 | ELANE (0.65) | ELANENPC1RAB9APPIA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1188401-C | Heterocyclic amide compound and its pharmaceutical use | MITSUBISHI PHARMACEUTICAL CO L (JP) | 2005-02-09 | — | — | CN | disclosed |
| CN-1131210-C | Heterocyclic amide compound and medical use thereof | MITSUBISHI SEIYAKU CO LTD (JP) | 2003-12-17 | — | — | CN | disclosed |
| CN-1304931-A | Heterocyclic amide compound and medical use thereof | EFUKU CO LTD (JP) | 2001-07-25 | — | — | CN | disclosed |
| US-5948785-A | USEFUL AS CHYMASE INHIBITORS AND CAN BE EFFECTIVE FOR THE PROPHYLAXIS AND TREATMENT OF VARIOUS DISEASES CAUSED BY CHYMASE, SUCH AS THOSE CAUSED BY ANGIOTENSIN II. | THE GREEN CROSS CORPORATION (JP) | 1999-09-07 | — | — | US | disclosed |
| CN-1188472-A | Heterocyclic amide compound and medical use thereof | GREEN CROSS CORP (JP) | 1998-07-22 | — | — | CN | disclosed |