Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 15/20 | 0.59 |
| ▸ | TACR3 | P29371 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27451145 | 0.92 | ELANE (0.55) | ELANENPC1RAB9AMGLL | |
| SCHEMBL27467025 | 0.91 | ELANE (0.51) | ELANENPC1RAB9A | |
| SCHEMBL8401430 | 0.90 | ELANE (0.59) | ELANENPC1RAB9AMGLL | |
| SCHEMBL8401403 | 0.90 | ELANE (0.58) | ELANENPC1RAB9A | |
| SCHEMBL8401406 | 0.89 | ELANE (0.50) | ELANENPC1RAB9A | |
| SCHEMBL8401266 | 0.86 | ELANE (0.60) | ELANENPC1RAB9A | |
| SCHEMBL8405263 | 0.85 | ELANE (0.58) | ELANENPC1RAB9A | |
| SCHEMBL27466074 | 0.84 | ELANE (0.46) | ELANENPC1RAB9A | |
| SCHEMBL27467469 | 0.84 | NPC1 (0.52) | ELANENPC1RAB9AFAAHMGLL | |
| SCHEMBL6556284 | 0.84 | ELANE (0.71) | ELANETACR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5948785-A | USEFUL AS CHYMASE INHIBITORS AND CAN BE EFFECTIVE FOR THE PROPHYLAXIS AND TREATMENT OF VARIOUS DISEASES CAUSED BY CHYMASE, SUCH AS THOSE CAUSED BY ANGIOTENSIN II. | THE GREEN CROSS CORPORATION (JP) | 1999-09-07 | — | — | US | disclosed |