Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8402097 | 0.88 | CCKBR (0.38) | CCKBR | |
| SCHEMBL8399460 | 0.88 | CCKBR (0.38) | CCKBR | |
| SCHEMBL8399272 | 0.86 | CCKBR (0.37) | CCKBR | |
| SCHEMBL8398983 | 0.86 | CCKBR (0.37) | CCKBR | |
| SCHEMBL8398473 | 0.86 | CCKBR (0.32) | CCKBR | |
| SCHEMBL8403197 | 0.84 | CCKBR (0.39) | CCKBR | |
| SCHEMBL8401313 | 0.81 | CCKBR (0.40) | CCKBR | |
| SCHEMBL8402177 | 0.77 | CCKBR (0.48) | CCKBR | |
| SCHEMBL8402444 | 0.76 | CCKBR (0.49) | CCKBRMEN1KMT2AL3MBTL1 | |
| SCHEMBL8403211 | 0.76 | CCKBR (0.49) | CCKBRMEN1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711283-B1 | TETRAHYDRO-1H-BENZAZEPINONES AND HEXAHYDROAZEPINONES AS SELECTIVE CHOLECYSTOKININ-B RECEPTOR ANTAGONISTS | PFIZER (US) | 1999-06-16 | — | — | EP | disclosed |
| US-5618811-A | Tetrahydro-1H-benzazepinones and hexahydroazepinones as selective cholecystokinin-B receptor antagonists | PFIZER INC. (US) | 1997-04-08 | — | — | US | disclosed |