Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 9/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | CCKAR | P32238 | 3/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8399460 | 0.90 | CCKBR (0.38) | CCKBRALDH1A1GAACCKAR | |
| SCHEMBL8399272 | 0.86 | CCKBR (0.37) | CCKBR | |
| SCHEMBL8398983 | 0.86 | CCKBR (0.37) | CCKBR | |
| SCHEMBL8402097 | 0.86 | CCKBR (0.38) | CCKBR | |
| SCHEMBL8398473 | 0.85 | CCKBR (0.32) | CCKBR | |
| SCHEMBL8401329 | 0.84 | CCKBR (0.40) | CCKBR | |
| SCHEMBL8399432 | 0.79 | CCKBR (0.51) | CCKBRALDH1A1 | |
| SCHEMBL8913795 | 0.78 | CCKBR (0.51) | CCKBRALDH1A1 | |
| SCHEMBL8402177 | 0.77 | CCKBR (0.48) | CCKBR | |
| Potassium Ion SCHEMBL8400982 | 0.77 | CCKBR (0.43) | CCKBR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711283-B1 | TETRAHYDRO-1H-BENZAZEPINONES AND HEXAHYDROAZEPINONES AS SELECTIVE CHOLECYSTOKININ-B RECEPTOR ANTAGONISTS | PFIZER (US) | 1999-06-16 | — | — | EP | disclosed |