Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.43 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | LGALS9 | O00182 | 2/20 | 0.38 |
| ▸ | GJB2 | P29033 | 1/20 | 0.38 |
| ▸ | GJA1 | P17302 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.37 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8398372 | 0.84 | LGALS8 (0.42) | LGALS8NPC1RAB9AGJB2GJA1 | |
| SCHEMBL13129831 | 0.79 | LGALS8 (0.44) | ALDH1A1LMNALGALS8LGALS9CYP3A4 | |
| SCHEMBL1491891 | 0.78 | CYP3A4 (0.41) | SMN1; SMN2CYP2D6MEN1ALDH1A1KMT2A | |
| SCHEMBL1491946 | 0.77 | FGF2 (0.44) | CYP2D6ALDH1A1LMNACYP2C9CYP2C19 | |
| SCHEMBL13869149 | 0.76 | SSTR5 (0.48) | CYP2C19LGALS8LGALS3 | |
| SCHEMBL8328990 | 0.76 | SSTR5 (0.48) | CYP2C19LGALS8LGALS3 | |
| SCHEMBL19226966 | 0.76 | SSTR5 (0.48) | CYP2C19LGALS8LGALS3 | |
| SCHEMBL12157641 | 0.74 | KMT2A (0.41) | SMN1; SMN2MEN1ALDH1A1KMT2ALMNA | |
| SCHEMBL22677785 | 0.74 | SSTR1 (0.46) | CYP2D6ALDH1A1KMT2ALMNAMAPK1 | |
| SCHEMBL22677717 | 0.74 | SSTR1 (0.46) | CYP2D6ALDH1A1KMT2ALMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5874411-A | ANTIINFLAMMATORY | GLYCOMED INCORPORATED (US) | 1999-02-23 | — | — | US | disclosed |