Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGF2 | P09038 | 1/20 | 0.44 |
| ▸ | MDK | P21741 | 1/20 | 0.44 |
| ▸ | LGALS8 | O00214 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | TACR1 | P25103 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1491923 | 0.86 | FGF2 (0.43) | FGF2MDKLGALS8NPC1RAB9A | |
| SCHEMBL1491868 | 0.84 | LGALS8 (0.40) | LGALS8NPC1RAB9AALDH1A1CYP3A4 | |
| SCHEMBL1491891 | 0.81 | CYP3A4 (0.41) | LGALS8NPC1RAB9AALDH1A1CYP3A4 | |
| SCHEMBL15654703 | 0.79 | FGF2 (0.39) | FGF2MDKLGALS8NPC1RAB9A | |
| SCHEMBL2469248 | 0.78 | LGALS8 (0.35) | LGALS8ALDH1A1CYP2C19CYP2C9TP53 | |
| SCHEMBL14672600 | 0.77 | FGF2 (0.42) | FGF2MDKNPC1RAB9ATP53 | |
| SCHEMBL1491873 | 0.77 | SLC5A2 (0.42) | NPC1RAB9ACYP3A4CYP2D6TACR1 | |
| SCHEMBL8401392 | 0.77 | SMN1; SMN2 (0.43) | LGALS8NPC1RAB9AALDH1A1CYP3A4 | |
| SCHEMBL1971069 | 0.75 | PDPK1 (0.39) | FGF2MDKLGALS8ALDH1A1CYP2C19 | |
| SCHEMBL15481391 | 0.74 | LGALS3 (0.50) | FGF2MDKLGALS8NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7901687-B2 | Antibodies for the detection of Bacillus anthracis and vaccine against B. anthracis infections | ETH ZURICH (CH) | 2011-03-08 | — | — | US | disclosed |
| US-20090155299-A1 | Antibodies for the Detection of Bacillus Anthracis and Vaccine Against B. Anthracis Infections | SCHWEIZERISCHES TROPENINSTITUT (CH) | 2009-06-18 | — | — | US | disclosed |
| EP-2012821-A2 | ANTIBODIES FOR THE DETECTION OF BACILLUS ANTHRACIS AND VACCINE AGAINST B. ANTHRACIS INFECTIONS | ETH Zürich (CH) | 2009-01-14 | — | — | EP | disclosed |
| WO-2007125089-A2 | ANTIBODIES FOR THE DETECTION OF BACILLUS ANTHRACIS AND VACCINE AGAINST B. ANTHRACIS INFECTIONS | ETH Zürich (CH) | 2007-11-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090155299-A1 | Antibodies for the Detection of Bacillus Anthracis and Vaccine Against B. Anthracis Infections | ANTXR2, CERT1, DAD1 | FGF2 2980/4885MDK 3902/4885LGALS8 1200/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.