Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 8/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.41 |
| ▸ | F2 | P00734 | 2/20 | 0.39 |
| ▸ | PLG | P00747 | 2/20 | 0.39 |
| ▸ | PLAU | P00749 | 2/20 | 0.39 |
| ▸ | KLK1 | P06870 | 2/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.39 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | PLAT | P00750 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17710566 | 0.85 | SIGMAR1 (0.47) | SIGMAR1ALDH1A1KDM4EGAAMEN1 | |
| SCHEMBL2431069 | 0.85 | SIGMAR1 (0.55) | SIGMAR1ALDH1A1KDM4EGAAPTPN1 | |
| SCHEMBL8742588 | 0.83 | SIGMAR1 (0.59) | SIGMAR1ALDH1A1KDM4EGAAMEN1 | |
| SCHEMBL16628639 | 0.78 | ALDH1A1 (0.47) | SIGMAR1ALDH1A1KDM4EGAAMEN1 | |
| SCHEMBL16628505 | 0.78 | ALDH1A1 (0.47) | SIGMAR1ALDH1A1KDM4EGAAMEN1 | |
| SCHEMBL16628631 | 0.77 | ALDH1A1 (0.50) | SIGMAR1ALDH1A1KDM4EGAAMEN1 | |
| SCHEMBL16628641 | 0.77 | ALDH1A1 (0.50) | SIGMAR1ALDH1A1KDM4EGAAMEN1 | |
| SCHEMBL4981507 | 0.75 | SIGMAR1 (0.73) | SIGMAR1ALDH1A1KDM4EGAAMEN1 | |
| SCHEMBL1477760 | 0.74 | ALDH1A1 (0.44) | SIGMAR1ALDH1A1KDM4EGAAMEN1 | |
| SCHEMBL16628502 | 0.74 | ALDH1A1 (0.42) | SIGMAR1ALDH1A1KDM4EGAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0918460-A1 | METHODS OF TREATMENT OF EYE TRAUMA AND DISORDERS | CAMBRIDGE NEUROSCIENCE, INC. (US) | 1999-06-02 | — | — | EP | disclosed |
| WO-1998004131-A1 | METHODS OF TREATMENT OF EYE TRAUMA AND DISORDERS | CAMBRIDGE NEUROSCIENCE, INC. (US) | 1998-02-05 | — | — | WO | disclosed |