Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.50 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | DTYMK | P23919 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CDK1 | P06493 | 1/20 | 0.36 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4994224 | 0.84 | BCHE (0.48) | BCHEKDM1AGPR119GSK3BKDM4E | |
| SCHEMBL26628082 | 0.80 | BCHE (0.52) | BCHENOTUMOPRM1OPRK1OPRL1 | |
| SCHEMBL31274704 | 0.80 | BCHE (0.52) | BCHENOTUMOPRM1OPRK1OPRL1 | |
| SCHEMBL8016162 | 0.77 | NOTUM (0.63) | BCHENOTUMKDM1AGPR119HDAC1 | |
| SCHEMBL30828978 | 0.76 | BCHE (0.51) | BCHEKDM1AGPR119HDAC1HDAC6 | |
| SCHEMBL29541811 | 0.75 | NOTUM (0.62) | BCHENOTUMKDM1AGPR119HDAC1 | |
| SCHEMBL2419240 | 0.75 | NOTUM (0.62) | BCHENOTUMKDM1AGPR119HDAC1 | |
| SCHEMBL6650008 | 0.75 | BCHE (0.43) | BCHENOTUMKDM1ASCN9AMEN1 | |
| SCHEMBL6648372 | 0.75 | KDM1A (0.54) | BCHENOTUMKDM1AGPR119HDAC1 | |
| SCHEMBL6137592 | 0.75 | BCHE (0.47) | BCHEKDM1AGPR119KDM4EPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5994544-A | PRODUCING A 5H-CHROMENO(3,4-F)QUINOLINE | LIGAND PHARMACEUTICALS INCORPORATED (US) | 1999-11-30 | — | — | US | disclosed |