Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CCR1 | P32246 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MMP1 | P03956 | 2/20 | 0.31 |
| ▸ | MMP2 | P08253 | 2/20 | 0.31 |
| ▸ | MMP3 | P08254 | 2/20 | 0.31 |
| ▸ | MMP8 | P22894 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8399823 | 0.78 | GAA (0.48) | GAASMN1; SMN2LMNACCR1POLB | |
| Hydrochloric Acid SCHEMBL6988684 | 0.71 | GAA (0.49) | GAAALDH1A1L3MBTL1SMN1; SMN2POLB | |
| SCHEMBL27475770 | 0.71 | GAA (0.52) | GAAALDH1A1L3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL6979222 | 0.68 | CAPN1 (0.47) | GAALMNAMAPT | |
| SCHEMBL6981469 | 0.64 | MAPK1 (0.48) | GAAALDH1A1L3MBTL1LMNAMAPT | |
| SCHEMBL6355903 | 0.61 | ALDH1A1 (0.59) | GAAALDH1A1L3MBTL1SMN1; SMN2POLB | |
| SCHEMBL15808453 | 0.61 | GAA (0.58) | GAAALDH1A1L3MBTL1SMN1; SMN2POLB | |
| SCHEMBL15808452 | 0.60 | GAA (0.57) | GAAALDH1A1L3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL8617486 | 0.60 | CAPN1 (0.33) | GAAALDH1A1L3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL14276864 | 0.59 | GAA (0.61) | GAAALDH1A1L3MBTL1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5935959-A | CYSTEINE PROTEASE INHIBITORS | SENJU PHARMACEUTICAL CO., LTD. (JP) | 1999-08-10 | — | — | US | disclosed |