Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 7/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | CAPN9 | O14815 | 2/20 | 0.33 |
| ▸ | CTSB | P07858 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | CTSK | P43235 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | USP2 | O75604 | 2/20 | 0.31 |
| ▸ | CTSL | P07711 | 1/20 | 0.31 |
| ▸ | CTSH | P09668 | 1/20 | 0.31 |
| ▸ | CTSS | P25774 | 1/20 | 0.31 |
| ▸ | CTSC | P53634 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6979222 | 0.74 | CAPN1 (0.47) | CAPN1MAPK1GAACAPN9CTSB | |
| SCHEMBL6979227 | 0.65 | GAA (0.39) | CAPN1MAPK1GAACAPN9CTSB | |
| SCHEMBL27475770 | 0.64 | GAA (0.52) | GAAALDH1A1L3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL14025158 | 0.61 | GAA (0.61) | GAAALDH1A1L3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL8401649 | 0.60 | GAA (0.38) | GAAALDH1A1L3MBTL1SMN1; SMN2LMNA | |
| Hydrochloric Acid SCHEMBL6988684 | 0.59 | GAA (0.49) | GAAALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL11142722 | 0.58 | — | — | |
| SCHEMBL3285387 | 0.57 | ALDH1A1 (0.53) | GAAALDH1A1L3MBTL1SMN1; SMN2MAPT | |
| SCHEMBL12304197 | 0.57 | GAA (0.55) | MAPK1GAAALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL6069773 | 0.57 | CAPN1 (0.64) | CAPN1MAPK1CAPN9CTSBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0838460-A1 | PIPERAZINE DERIVATIVES AND USE OF THE SAME | Senju Pharmaceutical Co., Ltd. (JP) | 1998-04-29 | — | — | EP | disclosed |