Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 8/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.52 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.41 |
| ▸ | FDPS | P14324 | 2/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.36 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL118855 | 0.98 | DNM1 (0.55) | DNM1TSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL115491 | 0.98 | DNM1 (0.55) | DNM1TSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL3622952 | 0.93 | DNM1 (0.48) | DNM1TSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL115864 | 0.93 | DNM1 (0.62) | DNM1TSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL27310197 | 0.91 | DNM1 (0.46) | DNM1TSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL27995753 | 0.89 | DNM1 (0.50) | DNM1TSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL3622828 | 0.86 | DNM1 (0.46) | DNM1TSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL15829526 | 0.86 | DNM1 (0.50) | DNM1TSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL31338939 | 0.85 | TSHR (0.50) | TSHRSMPD1FDPSCES2LPAR1 | |
| SCHEMBL8082452 | 0.85 | TSHR (0.50) | TSHRSMPD1FDPSCES2LPAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5886185-A | ANTITUMOR AGENTS, ANTICARCINOGENIC AGENTS | DEVELOPMENT CENTER FOR BIOTECHNOLOY (TW) | 1999-03-23 | — | — | US | disclosed |