SCHEMBL8401709

SCHEMBL8401709

COc1c(C(C)(C)C)cc(C(C)O)cc1C1(C)CCCCC1

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
RARA P10276 2/20 0.31
RARB P10826 2/20 0.31
RARG P13631 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8519229 0.86
SCHEMBL8400789 0.85 RARB (0.35) RARARARBRARG
SCHEMBL8397549 0.82 TSHR (0.38) RARBRARG
SCHEMBL8399180 0.82 RARA (0.33) RARARARBRARG
SCHEMBL8400690 0.79 RARA (0.33) RARARARBRARG
SCHEMBL7940459 0.78 RARA (0.33) RARARARBRARG
SCHEMBL7940198 0.75 RARA (0.33) RARARARBRARG
SCHEMBL8401561 0.74 RARB (0.37) RARARARBRARG
SCHEMBL7940452 0.73 PTGDR (0.41) RARARARBRARG
SCHEMBL6567008 0.73 TNKS2 (0.36) RARARARBRARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5914361-A IMPART HEAT STABILITY TO ORGANIC MATERIALS, INCLUDING POLYOLEFINS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-06-22 US disclosed