SCHEMBL8399180

SCHEMBL8399180

COc1c(C)cc(C(C)O)cc1C1(C)CCCCC1

nearest known ligand 0.33

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
RARA P10276 2/20 0.33
RARB P10826 2/20 0.33
RARG P13631 2/20 0.33
GLA P06280 1/20 0.33
TSHR P16473 1/20 0.33
ALOX12 P18054 1/20 0.33
PTGDR Q13258 1/20 0.30
PTGDR2 Q9Y5Y4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8401420 0.85 GLA (0.33) RARARARBRARGGLATSHR
SCHEMBL8401582 0.84 AKR1C3 (0.39) RARARARBRARGTSHRPTGDR
SCHEMBL8400690 0.82 RARA (0.33) RARARARBRARGGLATSHR
SCHEMBL8401709 0.82 RARA (0.31) RARARARBRARG
SCHEMBL8399159 0.81 GLA (0.43) RARARARBRARGGLATSHR
SCHEMBL7933907 0.76 RARB (0.34) RARARARBRARGGLATSHR
SCHEMBL8397564 0.75 RARA (0.49) RARARARBRARGPTGDRPTGDR2
SCHEMBL7794974 0.74 RARB (0.49) RARARARBRARGPTGDRPTGDR2
SCHEMBL6567296 0.73 GLA (0.35) RARARARBRARGGLATSHR
SCHEMBL7933771 0.72 RARB (0.39) RARARARBRARGGLATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5914361-A IMPART HEAT STABILITY TO ORGANIC MATERIALS, INCLUDING POLYOLEFINS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-06-22 US disclosed