Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 4/20 | 0.57 |
| ▸ | ANPEP | P15144 | 4/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.34 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3973783 | 1.00 | MMP2 (0.57) | MMP2ANPEPTSHRPTPN1BRD4 | |
| SCHEMBL8404149 | 1.00 | MMP2 (0.57) | MMP2ANPEPTSHRPTPN1BRD4 | |
| SCHEMBL719488 | 0.87 | PTPN1 (0.52) | MMP2ANPEPPTPN1BRD4ALDH1A1 | |
| SCHEMBL719489 | 0.87 | PTPN1 (0.52) | MMP2ANPEPPTPN1BRD4ALDH1A1 | |
| SCHEMBL85062 | 0.87 | PTPN1 (0.52) | MMP2ANPEPPTPN1BRD4ALDH1A1 | |
| SCHEMBL8406475 | 0.86 | MMP2 (0.45) | MMP2ANPEPTSHRBRD4DPP4 | |
| SCHEMBL15083833 | 0.86 | MMP2 (0.57) | MMP2ANPEPPTPN1BRD4CYP19A1 | |
| SCHEMBL8404080 | 0.86 | MMP2 (0.57) | MMP2ANPEPBRD4CYP19A1ALDH1A1 | |
| SCHEMBL8404107 | 0.86 | MMP2 (0.57) | MMP2ANPEPBRD4CYP19A1ALDH1A1 | |
| SCHEMBL201253 | 0.86 | MMP2 (0.57) | MMP2ANPEPPTPN1BRD4CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5928933-A | SEPARATING RACEMIC MIXTURE BY ENANTIOSELECTIVELY HYDROLYZING THE ESTER OF THE L-ISOMER; CHEMICAL INTERMEDIATE FOR 4-HYDROXYPROLINE | E. I. DU PONT DE NEMOURS & COMPANY (US) | 1999-07-27 | — | — | US | disclosed |