Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7796484 | 0.95 | TSHR (0.50) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL275389 | 0.88 | TSHR (0.53) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL891129 | 0.87 | TSHR (0.56) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL18139779 | 0.85 | TSHR (0.59) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL18139085 | 0.85 | TSHR (0.59) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL18139561 | 0.85 | TSHR (0.59) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL18140763 | 0.85 | TSHR (0.59) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL36359 | 0.84 | THRB (0.48) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL15480 | 0.84 | TSHR (0.64) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL1759348 | 0.83 | TSHR (0.51) | TSHRTHRBPOLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0663619-B1 | Process for the preparation of an image using only dry steps | AGFA GEVAERT NV (BE) | 1999-06-16 | — | — | EP | disclosed |