Phosphoric Acid

Phosphoric Acid

SCHEMBL8402385

CCCCCCCCCCCCCCCCCCONCC.CCCCCCCCCCCCCCCCCCONCC.CCCCCCCCCCCCCCCCCCONCC.O=P(O)(O)O

nearest known ligand 0.53

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Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
LPAR3 Q9UBY5 12/20 0.53
LPAR2 Q9HBW0 7/20 0.53
LPAR1 Q92633 5/20 0.53
EPHX1 P07099 1/20 0.41
LPAR5 Q9H1C0 1/20 0.41
SMPD1 P17405 2/20 0.40
S1PR2 O95136 2/20 0.40
S1PR4 O95977 2/20 0.40
S1PR1 P21453 2/20 0.40
S1PR3 Q99500 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10606108 0.87 CA1 (0.43) LPAR3LPAR2LPAR1EPHX1
SCHEMBL1109711 0.87 CA1 (0.43) LPAR3LPAR2LPAR1EPHX1
SCHEMBL18628622 0.87 CA1 (0.43) LPAR3LPAR2LPAR1EPHX1
SCHEMBL11519105 0.87 CA1 (0.43) LPAR3LPAR2LPAR1EPHX1
SCHEMBL9766772 0.87 CA1 (0.43) LPAR3LPAR2LPAR1EPHX1
SCHEMBL10520128 0.87 CA1 (0.43) LPAR3LPAR2LPAR1EPHX1
SCHEMBL21314157 0.85
SCHEMBL309203 0.78
SCHEMBL19349603 0.78 LPAR3 (0.55) LPAR3LPAR2LPAR1EPHX1LPAR5
SCHEMBL27934271 0.78 LPAR3 (0.55) LPAR3LPAR2LPAR1EPHX1LPAR5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0584692-B1 Cleaning and conditioning agent for hair, skin as well as for textiles and hard surfaces MAEURER & WIRTZ GMBH & CO KG (DE) 1999-06-16 EP disclosed
EP-0584692-A2 Cleaning and conditioning agent for hair, skin as well as for textiles and hard surfaces MÄURER + WIRTZ GmbH & Co. KG (DE) 1994-03-02 EP disclosed