SCHEMBL840288

SCHEMBL840288

CCCNC(F)(F)F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL28213190 0.97
SCHEMBL1995724 0.81
Hydrochloric Acid SCHEMBL6888353 0.73
SCHEMBL27197660 0.72 ADH1B (0.33)
SCHEMBL839397 0.72
Hydrochloric Acid SCHEMBL28228006 0.69
SCHEMBL271217 0.69
SCHEMBL3626775 0.68 LMNA (0.31)
SCHEMBL11790131 0.68
Hydrochloric Acid SCHEMBL28241516 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 82 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8143408-B2 N-(8-heteroaryltetrahydronaphtalene-2yl) or N-(5-heteroarylchromane-3-yl) carboxamide derivatives for the treatment of pain ASTRAZENECA AB (SE) 2012-03-27 US claimed
US-20100137322-A1 NOVEL N-(8-HETEROARYLTETRAHYDRONAPHTALENE-2YL) OR N-(5-HETEROARYLCHROMANE-3-YL) CARBOXAMIDE DERIVATIVES FOR THE TREATMENT OF PAIN ASTRAZENECA AB (SE) 2010-06-03 US claimed
CN-113874426-B Water-soluble film and package 株式会社可乐丽 2025-03-28 CN disclosed
CN-112147731-B Optical filter, solid-state imaging device, and camera module JSR株式会社 2023-12-05 CN disclosed
CN-111868579-B Optical filter and use thereof JSR株式会社 2022-08-09 CN disclosed
CN-113874426-A Water-soluble film and package 株式会社可乐丽 2021-12-31 CN disclosed
CN-112794788-B Method for synthesizing fluoroisobutylene by using hexafluoropropylene as starting material 泉州宇极新材料科技有限公司 2021-07-09 CN disclosed
CN-112794788-A Method for synthesizing fluoroisobutylene by using hexafluoropropylene as starting material 北京宇极科技发展有限公司 2021-05-14 CN disclosed
CN-112147731-A Optical filter, solid-state imaging device, camera module, biometric authentication device, and resin layer for optical filter JSR株式会社 2020-12-29 CN disclosed
CN-111868579-A Optical filter and use thereof JSR株式会社 2020-10-30 CN disclosed
WO-2020218321-A1 WATER-SOLUBLE FILM AND PACKAGING 株式会社クラレ 2020-10-29 WO disclosed
WO-2004065391-A1 4-AMINOTHIENO[2,3-d]PYRIMIDINE-6-CARBONITRILE DERIVATIVES AS PDE7 INHIBITORS ALMIRALL PRODESFARMA S.A. (ES) 2004-08-05 WO disclosed
WO-2004058729-A1 NEW PYRIDAZIN-3(2H)-ONE DERIVATIVES ALMIRALL PRODESFARMA SA (ES) 2004-07-15 WO disclosed
WO-2004043966-A1 NEW TRICYCLIC DERIVATIVES AS LTD4 ANTAGONISTS ALMIRALL PRODESFARMA S.A. (ES) 2004-05-27 WO disclosed
CN-1477995-A Fluorinated zwitterionic cocatalyst activators for olefin polymerization 埃克森美孚化学专利公司 2004-02-25 CN disclosed
EP-0819000-A4 NODULISPORIC ACID DERIVATIVES MERCK & CO INC (US) 2001-04-11 EP disclosed
US-5962499-A ACARICIDAL, ANTIPARASITIC, INSECTICIDAL AND ANTHELMINTIC AGENTS MERCK & CO., INC. (US) 1999-10-05 US disclosed
EP-0819000-A1 NODULISPORIC ACID DERIVATIVES Merck & Co., Inc. (US) 1998-01-21 EP disclosed
WO-1996029073-A1 NODULISPORIC ACID DERIVATIVES MERCK & CO., INC. (US) 1996-09-26 WO disclosed
WO-1995006642-A1 MALODINITRIL-SUBSTITUTED 1,3,5-TRIAZIN-DIAMINES WITH HERBICIDAL ACTIVITY BAYER AKTIENGESELLSCHAFT (DE) 1995-03-09 WO disclosed