SCHEMBL8403279

SCHEMBL8403279

O=C(Nc1ccccc1)c1ccc(NC(=O)c2cc3ccccc3cc2O)cc1

nearest known ligand 0.80

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 6/20 0.71
RAB9A P51151 5/20 0.71
MEN1 O00255 5/20 0.71
NPC1 O15118 4/20 0.71
POLB P06746 4/20 0.71
PLG P00747 3/20 0.69
PLAU P00749 2/20 0.69
F2 P00734 1/20 0.69
F10 P00742 1/20 0.69
PLAT P00750 1/20 0.69
CASP3 P42574 1/20 0.68
SENP7 Q9BQF6 1/20 0.68
SENP6 Q9GZR1 1/20 0.68
KLK1 P06870 2/20 0.66
KLK6 Q92876 2/20 0.66
MAPT P10636 3/20 0.63
MAPK1 P28482 2/20 0.63
APOBEC3A P31941 1/20 0.63
APOBEC3G Q9HC16 1/20 0.63
TNF P01375 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10597427 0.95 KMT2A (0.73) KMT2ARAB9AMEN1NPC1POLB
SCHEMBL30084384 0.92 MEN1 (0.77) KMT2ARAB9AMEN1NPC1POLB
SCHEMBL57970 0.92 MEN1 (0.77) KMT2ARAB9AMEN1NPC1POLB
SCHEMBL29890853 0.92 MEN1 (0.77) KMT2ARAB9AMEN1NPC1POLB
SCHEMBL7822238 0.91 KMT2A (0.71) KMT2ARAB9AMEN1NPC1POLB
SCHEMBL5426499 0.91 KMT2A (0.84) KMT2ARAB9AMEN1NPC1POLB
SCHEMBL6575251 0.90 PLAU (0.64) KMT2ARAB9AMEN1NPC1POLB
SCHEMBL10748621 0.89 KMT2A (0.73) KMT2ARAB9AMEN1NPC1POLB
SCHEMBL14585765 0.89 MEN1 (0.72) KMT2ARAB9AMEN1NPC1POLB
Phosphoric Acid SCHEMBL15485900 0.88 MEN1 (0.70) KMT2ARAB9AMEN1NPC1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0628881-B1 An organic photoconductive material and photosensitive material for electronic photography using it DAINICHISEIKA COLOR CHEM (JP) 1999-06-23 EP disclosed
US-5569749-A AZO COMPOUND AS CARRIER GENERATING SUBSTANCE DAINICHISEIKA COLOR & CHEMICALS MFG. CO., LTD. (JP) 1996-10-29 US disclosed
US-5506346-A CARRIER GENERATING SUBSTANCE HAVING HIGH PERFORMANCE AND DURABILITY DAINICHISEIKA COLOR & CHEMICALS MFG. CO., LTD. (JP) 1996-04-09 US disclosed
EP-0628881-A2 An organic photoconductive material and photosensitive material for electronic photography using it DAINICHISEIKA COLOR & CHEMICALS MFG. CO. LTD. (JP) 1994-12-14 EP disclosed