SCHEMBL8403294

SCHEMBL8403294

CC[C@@H](NC(C)=O)c1ccc(Cl)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.53
LMNA P02545 2/20 0.53
SMN1; SMN2 Q16637 1/20 0.53
TAS1R3 Q7RTX0 1/20 0.49
TAS1R1 Q7RTX1 1/20 0.49
HTT P42858 1/20 0.49
BRD4 O60885 1/20 0.46
MAPK1 P28482 1/20 0.45
ACACB O00763 1/20 0.44
TSHR P16473 2/20 0.44
CNR2 P34972 1/20 0.44
UTS2R Q9UKP6 3/20 0.43
MEN1 O00255 1/20 0.43
CYP1A2 P05177 1/20 0.43
CYP3A4 P08684 1/20 0.43
CYP2D6 P10635 1/20 0.43
CYP2C9 P11712 1/20 0.43
CYP2C19 P33261 1/20 0.43
KMT2A Q03164 1/20 0.43
KDM4E B2RXH2 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8398268 1.00 ALDH1A1 (0.53) ALDH1A1LMNASMN1; SMN2TAS1R3TAS1R1
SCHEMBL185572 0.84 ALDH1A1 (0.68) ALDH1A1LMNASMN1; SMN2TAS1R3TAS1R1
SCHEMBL5988629 0.83 ALDH1A1 (0.54) ALDH1A1LMNASMN1; SMN2ACACBTSHR
SCHEMBL15655244 0.83 CYP26A1 (0.58) LMNATSHRMEN1CYP1A2CYP3A4
SCHEMBL1697588 0.82 CYP1A2 (0.65) ALDH1A1LMNASMN1; SMN2HTTACACB
SCHEMBL7081080 0.82 ALDH1A1 (0.49) ALDH1A1LMNASMN1; SMN2TAS1R3TAS1R1
SCHEMBL186416 0.81 LMNA (0.61) ALDH1A1LMNASMN1; SMN2TAS1R3TAS1R1
SCHEMBL186238 0.81 LMNA (0.61) ALDH1A1LMNASMN1; SMN2TAS1R3TAS1R1
SCHEMBL186230 0.81 LMNA (0.61) ALDH1A1LMNASMN1; SMN2TAS1R3TAS1R1
SCHEMBL21009509 0.80 ATM (0.51) BRD4ACACBCNR2UTS2RCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5952527-A A COMPLEX OF TRANSITIONAL METAL COMPOUND, CYCLOOCTADIENE OR CYCLOPENTADIENE AND 2,2-BIS/DIPHENYLPHOSPHINOAMINO/-5,5',6,6'7,7',8,8'-OCTAHYDRO-1 ,1'-BINAPHTHYL COMPOUND; USED AS HYDROGENATION CATALYST THE HONG KONG POLYTECHNIC UNIVERSITY (HK) 1999-09-14 US disclosed
US-5919981-A USING HYDROGENATION 1,1*-BINAPHTHYL-2,2*-DIAMINE AS CHEMICAL INTERMEDIATE THE HONG KONG POLYTECHNIC UNIVERSITY (HK) 1999-07-06 US disclosed