Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 4/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | DRD4 | P21917 | 3/20 | 0.60 |
| ▸ | DRD2 | P14416 | 3/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | DRD3 | P35462 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | HRH2 | P25021 | 1/20 | 0.54 |
| ▸ | HRH1 | P35367 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9720648 | 0.84 | HTR7 (0.70) | HTR7ALDH1A1MAPK1DRD4DRD2 | |
| SCHEMBL8406351 | 0.84 | ALDH1A1 (0.68) | ALDH1A1MAPK1DRD4DRD2KDM4E | |
| SCHEMBL7691290 | 0.81 | ALDH1A1 (0.71) | HTR7ALDH1A1MAPK1DRD4DRD2 | |
| SCHEMBL9720681 | 0.80 | MAPK1 (0.78) | HTR7ALDH1A1MAPK1DRD4DRD2 | |
| SCHEMBL9720708 | 0.80 | DRD4 (0.73) | HTR7ALDH1A1MAPK1DRD4DRD2 | |
| SCHEMBL9720726 | 0.79 | KDM4E (0.79) | HTR7ALDH1A1MAPK1DRD4DRD2 | |
| SCHEMBL9720699 | 0.79 | HTR7 (0.65) | HTR7ALDH1A1MAPK1DRD4DRD2 | |
| SCHEMBL9225440 | 0.77 | MAPK1 (0.81) | HTR7ALDH1A1MAPK1DRD4DRD2 | |
| SCHEMBL6131943 | 0.77 | KDM4E (0.63) | HTR7ALDH1A1MAPK1DRD4DRD2 | |
| SCHEMBL6031726 | 0.76 | MAPK1 (0.80) | HTR7ALDH1A1MAPK1DRD4DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1072655-C | New heterocyclic aminomethyl compounds, process for preparing them and pharmaceutical compositions containing them | ADIR (FR) | 2001-10-10 | — | — | CN | disclosed |
| US-5919784-A | ANXIETY, DEPRESSION | ADIR ET COMPAGNIE (FR) | 1999-07-06 | — | — | US | disclosed |
| CN-1182083-A | New heterocyclic aminomethyl compounds, process for preparing them and pharmaceutical compositions containing them | ADIR (FR) | 1998-05-20 | — | — | CN | disclosed |
| EP-0841330-A1 | Aminomethyl heterocyclic derivatives, process of their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1998-05-13 | — | — | EP | disclosed |
| EP-0839133-A1 | 4,9-ETHANO-BENZO(F)ISOINDOLE DERIVATIVES AS FARNESYL TRANSFERASE INHIBITORS | Aventis Pharma S.A. (FR) | 1998-05-06 | — | — | EP | disclosed |
| WO-1997003050-A1 | 4,9-ETHANO-BENZO(F)ISOINDOLE DERIVATIVES AS FARNESYL TRANSFERASE INHIBITORS | RHONE-POULENC RORER S.A. (FR) | 1997-01-30 | — | — | WO | disclosed |