Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1D1 | P20393 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MMP2 | P08253 | 2/20 | 0.40 |
| ▸ | ANPEP | P15144 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8401731 | 1.00 | NR1D1 (0.42) | NR1D1ALDH1A1MAPTMMP2ANPEP | |
| SCHEMBL8401928 | 1.00 | NR1D1 (0.42) | NR1D1ALDH1A1MAPTMMP2ANPEP | |
| SCHEMBL8405574 | 0.93 | NR1D1 (0.39) | NR1D1ALDH1A1MAPTMMP2ANPEP | |
| SCHEMBL8273056 | 0.90 | PTPN1 (0.41) | NR1D1ALDH1A1MAPTMMP2ANPEP | |
| SCHEMBL9273462 | 0.90 | PTPN1 (0.41) | NR1D1ALDH1A1MAPTMMP2ANPEP | |
| SCHEMBL8293214 | 0.85 | NPSR1 (0.48) | NR1D1KDM4EHPGDFKBP1AL3MBTL1 | |
| SCHEMBL8863381 | 0.85 | NPSR1 (0.48) | NR1D1KDM4EHPGDFKBP1AL3MBTL1 | |
| SCHEMBL27844684 | 0.78 | MMP2 (0.46) | ALDH1A1MMP2ANPEPKMT2AFKBP1A | |
| SCHEMBL14918089 | 0.78 | MMP2 (0.46) | ALDH1A1MMP2ANPEPKMT2AFKBP1A | |
| SCHEMBL29409301 | 0.77 | NR1D1 (0.68) | NR1D1ALDH1A1GAAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5928933-A | SEPARATING RACEMIC MIXTURE BY ENANTIOSELECTIVELY HYDROLYZING THE ESTER OF THE L-ISOMER; CHEMICAL INTERMEDIATE FOR 4-HYDROXYPROLINE | E. I. DU PONT DE NEMOURS & COMPANY (US) | 1999-07-27 | — | — | US | disclosed |