Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOS1 | Q07889 | 2/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 9/20 | 0.38 |
| ▸ | CA1 | P00915 | 8/20 | 0.38 |
| ▸ | CA9 | Q16790 | 8/20 | 0.38 |
| ▸ | CA12 | O43570 | 7/20 | 0.37 |
| ▸ | CA4 | P22748 | 2/20 | 0.37 |
| ▸ | CA6 | P23280 | 2/20 | 0.37 |
| ▸ | CA5A | P35218 | 2/20 | 0.37 |
| ▸ | CA7 | P43166 | 2/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.37 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.37 |
| ▸ | CA3 | P07451 | 1/20 | 0.37 |
| ▸ | PTGES2 | Q9H7Z7 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8404555 | 1.00 | SOS1 (0.39) | SOS1PTGS1PTGS2CA2CA1 | |
| SCHEMBL8404551 | 0.88 | KDM4E (0.41) | SOS1PTGS1PTGS2CA2CA1 | |
| SCHEMBL8404547 | 0.88 | CA1 (0.42) | CA2CA1CA9CA12CA4 | |
| SCHEMBL8404545 | 0.85 | PTGS2 (0.37) | PTGS1PTGS2L3MBTL1ALDH1A1 | |
| SCHEMBL8404747 | 0.85 | PTGS2 (0.37) | PTGS1PTGS2L3MBTL1ALDH1A1 | |
| SCHEMBL8408242 | 0.81 | KDM1A (0.40) | SOS1PTGS1PTGS2CA2CA1 | |
| SCHEMBL8408244 | 0.81 | CA1 (0.38) | CA2CA1CA9CA12CA4 | |
| SCHEMBL8408243 | 0.81 | CA1 (0.38) | CA2CA1CA9CA12CA4 | |
| SCHEMBL8404542 | 0.81 | KDM1A (0.40) | SOS1PTGS1PTGS2CA2CA1 | |
| SCHEMBL8404318 | 0.75 | CA12 (0.50) | SOS1PTGS1PTGS2CA2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040116399-A1 | Inhibitors of factor Xa | MILLENNIUM PHARMACEUTICALS, INC. | 2004-06-17 | — | — | US | disclosed |