Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 11/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CCR2 | P41597 | 2/20 | 0.35 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | IDH1 | O75874 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8404747 | 1.00 | PTGS2 (0.37) | PTGS2L3MBTL1CCR2AGTR1ALDH1A1 | |
| SCHEMBL8404745 | 0.87 | L3MBTL1 (0.42) | PTGS2L3MBTL1CCR2ALDH1A1 | |
| SCHEMBL8404548 | 0.87 | L3MBTL1 (0.42) | L3MBTL1ALDH1A1 | |
| SCHEMBL8404555 | 0.85 | SOS1 (0.39) | PTGS2L3MBTL1ALDH1A1PTGS1 | |
| SCHEMBL8404552 | 0.85 | SOS1 (0.39) | PTGS2L3MBTL1ALDH1A1PTGS1 | |
| SCHEMBL8404549 | 0.79 | L3MBTL1 (0.37) | L3MBTL1CCR2ALDH1A1 | |
| SCHEMBL8404543 | 0.79 | L3MBTL1 (0.37) | L3MBTL1CCR2ALDH1A1 | |
| SCHEMBL8404540 | 0.79 | L3MBTL1 (0.37) | PTGS2L3MBTL1CCR2AGTR1ALDH1A1 | |
| SCHEMBL8404546 | 0.79 | L3MBTL1 (0.37) | PTGS2L3MBTL1CCR2AGTR1ALDH1A1 | |
| SCHEMBL8404319 | 0.74 | L3MBTL1 (0.42) | PTGS2L3MBTL1CCR2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040116399-A1 | Inhibitors of factor Xa | MILLENNIUM PHARMACEUTICALS, INC. | 2004-06-17 | — | — | US | disclosed |