Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 18/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8403235 | 0.92 | CCKBR (0.52) | CCKBR | |
| SCHEMBL8402077 | 0.90 | CCKBR (0.64) | CCKBR | |
| SCHEMBL8402133 | 0.85 | CCKBR (0.41) | CCKBR | |
| SCHEMBL8399432 | 0.84 | CCKBR (0.51) | CCKBRALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL8402188 | 0.84 | CCKBR (0.40) | CCKBR | |
| SCHEMBL8402172 | 0.84 | CCKBR (0.41) | CCKBR | |
| SCHEMBL8913795 | 0.84 | CCKBR (0.51) | CCKBRALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL8398505 | 0.83 | CCKBR (0.41) | CCKBR | |
| SCHEMBL8403246 | 0.83 | CCKBR (0.43) | CCKBR | |
| SCHEMBL8402155 | 0.83 | CCKBR (0.65) | CCKBR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711283-B1 | TETRAHYDRO-1H-BENZAZEPINONES AND HEXAHYDROAZEPINONES AS SELECTIVE CHOLECYSTOKININ-B RECEPTOR ANTAGONISTS | PFIZER (US) | 1999-06-16 | — | — | EP | disclosed |
| US-5618811-A | Tetrahydro-1H-benzazepinones and hexahydroazepinones as selective cholecystokinin-B receptor antagonists | PFIZER INC. (US) | 1997-04-08 | — | — | US | disclosed |