SCHEMBL8404844

SCHEMBL8404844

Cc1ccc(-n2c(NS(=O)(=O)c3ccccc3)csc2=O)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.49
GAA P10253 2/20 0.49
CYP2C9 P11712 3/20 0.48
CYP2C19 P33261 2/20 0.48
CA12 O43570 2/20 0.47
CA2 P00918 2/20 0.47
CA9 Q16790 2/20 0.47
CA1 P00915 1/20 0.47
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
MAPT P10636 2/20 0.43
FFAR4 Q5NUL3 1/20 0.42
L3MBTL1 Q9Y468 3/20 0.41
LMNA P02545 2/20 0.41
POLB P06746 2/20 0.41
USP2 O75604 1/20 0.41
NOD2 Q9HC29 1/20 0.41
KEAP1 Q14145 1/20 0.41
NFE2L2 Q16236 1/20 0.41
MCOLN3 Q8TDD5 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8504989 0.79 CYP2C9 (0.53) ALDH1A1GAACYP2C9CYP2C19CA12
SCHEMBL8504924 0.72 CYP2C9 (0.52) ALDH1A1GAACYP2C9CYP2C19CA12
SCHEMBL8502466 0.71 CYP2C9 (0.53) ALDH1A1GAACYP2C9CYP2C19CA12
SCHEMBL8506063 0.69 CYP2C9 (0.51) ALDH1A1GAACYP2C9CYP2C19MEN1
SCHEMBL8502313 0.69 ALDH1A1 (0.49) ALDH1A1GAACYP2C9CYP2C19MEN1
SCHEMBL8504469 0.69 TSHR (0.48) ALDH1A1GAACYP2C9MEN1KMT2A
SCHEMBL8504983 0.68 FFAR4 (0.46) ALDH1A1CYP2C9CYP2C19CA12CA2
SCHEMBL4616053 0.68 CYP1A2 (0.61) ALDH1A1GAACYP2C19MEN1KMT2A
SCHEMBL806766 0.68 CA12 (0.85) ALDH1A1GAACA12CA2CA9
SCHEMBL4963084 0.68 CYP2C9 (0.52) ALDH1A1GAACYP2C9CYP2C19MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5859036-A ANTIINFLAMMATORY AGENTS, ANALGESICS LABORATORIES UPSA (FR) 1999-01-12 US disclosed