SCHEMBL8405010

SCHEMBL8405010

Oc1ccc(C2=CCC2)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
QDPR P09417 2/20 0.56
ESR1 P03372 6/20 0.53
ESR2 Q92731 5/20 0.53
MEN1 O00255 4/20 0.44
KMT2A Q03164 4/20 0.44
NPC1 O15118 2/20 0.44
MAPT P10636 2/20 0.44
NFKB1 P19838 2/20 0.44
RAB9A P51151 2/20 0.44
KDM4E B2RXH2 1/20 0.44
CA12 O43570 1/20 0.44
GMNN O75496 1/20 0.44
ALDH1A1 P00352 1/20 0.44
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
LMNA P02545 1/20 0.44
CA3 P07451 1/20 0.44
CYP3A4 P08684 1/20 0.44
TYR P14679 1/20 0.44
HPGD P15428 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6757113 0.82 ACMSD (0.53) QDPRESR1ESR2MEN1KMT2A
SCHEMBL188943 0.80 MEN1 (0.55) QDPRESR1ESR2MEN1KMT2A
SCHEMBL28347432 0.80 ESR1 (0.56) QDPRESR1ESR2MEN1KMT2A
SCHEMBL10581819 0.79 MEN1 (0.54) QDPRESR1ESR2MEN1KMT2A
SCHEMBL11655788 0.79 MEN1 (0.54) QDPRESR1ESR2MEN1KMT2A
SCHEMBL11655792 0.79 MEN1 (0.54) QDPRESR1ESR2MEN1KMT2A
SCHEMBL2719790 0.78 ESR1 (0.53) QDPRESR1ESR2MEN1KMT2A
SCHEMBL28161071 0.76 BACE1 (0.42) QDPRESR2NPC1RAB9ACA12
SCHEMBL2720984 0.74 ESR1 (0.56) QDPRESR1ESR2MEN1KMT2A
SCHEMBL9123640 0.74 HSD17B1 (0.54) ESR1ESR2CA12ALDH1A1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 80 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5616765-A Method for the preparation of 4-hydroxy-and 4-trimethylsiloxybenzocyclobutene THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) 1997-04-01 US claimed
EP-0612351-A1 MICROBIAL PRODUCTION OF CIS-DIHYDRODIOL AND PHENOL DERIVATIVES OF BENZOCYCLOBUTENE BIO-TECHNICAL RESOURCES, INC. (US) 1994-08-31 EP claimed
EP-0604575-A1 PROCESS FOR PREPARING HYDROXYBENZOCYCLOBUTENES THE DOW CHEMICAL COMPANY (US) 1994-07-06 EP claimed
US-5227536-A PROCESS FOR PREPARING HYDROXYBENZOCYCLOBUTENES THE DOW CHEMICAL COMPANY (US) 1993-07-13 US claimed
WO-1993009241-A1 MICROBIAL PRODUCTION OF CIS-DIHYDRODIOL AND PHENOL DERIVATIVES OF BENZOCYCLOBUTENE BIO-TECHNICAL RESOURCES (US) 1993-05-13 WO claimed
WO-1993006072-A1 PROCESS FOR PREPARING HYDROXYBENZOCYCLOBUTENES THE DOW CHEMICAL COMPANY (US) 1993-04-01 WO claimed
CN-119930994-A Crosslinkable hole-transport polymer and application thereof 东莞伏安光电科技有限公司 2025-05-06 CN disclosed
CN-115583889-B Diamine, liquid crystal aligning agent, and preparation method and application thereof 波米科技有限公司 2023-09-19 CN disclosed
CN-115639724-B Preparation method and application of photosensitive resin composition 波米科技有限公司 2023-08-08 CN disclosed
CN-114805660-B Synthesis of functionalized trifluoro vinyl compound and preparation method of resin thereof 中国科学院化学研究所 2023-06-06 CN disclosed
CN-115639724-A Preparation method and application of photosensitive resin composition 波米科技有限公司 2023-01-24 CN disclosed
CN-115583889-A Diamine, liquid crystal aligning agent, and preparation method and application thereof 波米科技有限公司 2023-01-10 CN disclosed
CN-114805660-A Synthesis of functionalized trifluorovinyl compound and resin preparation method thereof 中国科学院化学研究所 2022-07-29 CN disclosed
WO-1993006072-A1 PROCESS FOR PREPARING HYDROXYBENZOCYCLOBUTENES THE DOW CHEMICAL COMPANY (US) 1993-04-01 WO disclosed
US-5198527-A Arylcyclobutene terminated carbonate polymer THE DOW CHEMICAL COMPANY (US) 1993-03-30 US disclosed
US-5171824-A Polymerizing precursors of polycarbonate, polyester or polyestercarbonate compound along with multihydric compounds and benzocyclobutene derivatives THE DOW CHEMICAL COMPANY (US) 1992-12-15 US disclosed
US-5156656-A Gas separation THE DOW CHEMICAL COMPANY (US) 1992-10-20 US disclosed
WO-1992011309-A1 ARYLCYCLOBUTENE TERMINATED CARBONATE POLYMERS THE DOW CHEMICAL COMPANY (US) 1992-07-09 WO disclosed
WO-1992011308-A1 PROCESS FOR THE PREPARATION OF ARYLCYCLOBUTENE TERMINATED CONDENSATION POLYMERS THE DOW CHEMICAL COMPANY (US) 1992-07-09 WO disclosed
US-4675370-A Resin systems derived from benzocyclobutene-alkyne imide monomers UNIVERSITY OF DAYTON (US) 1987-06-23 US disclosed