Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK1 | Q13464 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | MKNK1 | Q9BUB5 | 3/20 | 0.43 |
| ▸ | MKNK2 | Q9HBH9 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.41 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29721693 | 0.74 | ROCK1 (0.61) | ROCK1TP53LMNAMAPK1NPC1 | |
| SCHEMBL3239758 | 0.74 | ROCK1 (0.61) | ROCK1TP53LMNAMAPK1NPC1 | |
| Hydrochloric Acid SCHEMBL27693256 | 0.73 | ROCK1 (0.59) | ROCK1TP53LMNAMAPK1NPC1 | |
| SCHEMBL1019181 | 0.71 | NPC1 (0.49) | ROCK1TP53LMNAMAPK1NPC1 | |
| SCHEMBL29721478 | 0.71 | ROCK1 (0.62) | ROCK1TP53LMNAMAPK1NPC1 | |
| SCHEMBL6071629 | 0.71 | ROCK1 (0.62) | ROCK1TP53LMNAMAPK1NPC1 | |
| SCHEMBL9377412 | 0.70 | ROCK1 (1.00) | ROCK1MKNK1MKNK2MAPK8MAPK9 | |
| SCHEMBL4971770 | 0.70 | FAAH (0.35) | ROCK1 | |
| SCHEMBL8121028 | 0.69 | ROCK1 (0.55) | ROCK1TP53LMNAMAPK1NPC1 | |
| SCHEMBL15831287 | 0.69 | ROCK1 (0.55) | ROCK1TP53LMNAMAPK1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5929227-A | DNA FLUORESCENT STAINS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1999-07-27 | — | — | US | disclosed |
| US-5760201-A | Dimeric fluorescent energy transfer dyes comprising asymmetric cyanine azole-indolenine chromophores | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1998-06-02 | — | — | US | disclosed |
| US-5565554-A | DNA-STAINING FLUORECENCENT DYES, USED IN GEL ELECTROPHORESIS AND FOR LABELS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1996-10-15 | — | — | US | disclosed |
| WO-1996004405-A1 | NOVEL DIMERIC FLUORESCENT ENERGY TRANSFER DYES COMPRISING ASYMMETRIC CYANINE AZOLE-INDOLENINE CHROMOPHORES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1996-02-15 | — | — | WO | disclosed |