Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.49 |
| ▸ | RAB9A | P51151 | 5/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.46 |
| ▸ | SRD5A1 | P18405 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12283641 | 0.79 | SRD5A1 (0.50) | SRD5A1LMNAMAPK1ALDH1A1HTT | |
| SCHEMBL11459166 | 0.76 | NPC1 (0.41) | NPC1RAB9ATDP1MAPK1ALDH1A1 | |
| SCHEMBL9489951 | 0.72 | KDM4E (0.37) | NPC1RAB9ATDP1SRD5A1ALDH1A1 | |
| SCHEMBL8405088 | 0.71 | ROCK1 (0.54) | NPC1RAB9ATDP1ROCK1SRD5A1 | |
| SCHEMBL29264505 | 0.71 | PIM1 (0.46) | NPC1RAB9ATDP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL29542545 | 0.71 | ALDH1A1 (0.53) | NPC1RAB9ATDP1ROCK1SRD5A1 | |
| SCHEMBL3905172 | 0.71 | ALDH1A1 (0.53) | NPC1RAB9ATDP1ROCK1SRD5A1 | |
| SCHEMBL1021868 | 0.70 | CD74 (0.53) | NPC1RAB9AROCK1SRD5A1LMNA | |
| SCHEMBL11445531 | 0.70 | ALDH1A1 (0.67) | NPC1RAB9ATDP1LMNATP53 | |
| SCHEMBL19117986 | 0.69 | SRD5A1 (0.56) | NPC1RAB9AROCK1SRD5A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0010063-B1 | PROCESS FOR THE PREPARATION OF FURANYL-BENZAZOLES | CIBA-GEIGY AG (CH) | 1982-12-29 | — | — | EP | claimed |
| EP-0010063-A2 | Process for the preparation of furanyl-benzazoles | CIBA-GEIGY AG (CH) | 1980-04-16 | — | — | EP | claimed |
| EP-2271306-A1 | DECORATIVE COSMETIC COMPOSITIONS | Bayer MaterialScience AG (DE) | 2011-01-12 | — | — | EP | disclosed |
| EP-2271305-A1 | SUN PROTECTION COMPOSITIONS | Bayer MaterialScience AG (DE) | 2011-01-12 | — | — | EP | disclosed |
| WO-2009118103-A1 | SUN PROTECTION COMPOSITIONS | BAYER MATERIALSCIENCE AG (DE) | 2009-10-01 | — | — | WO | disclosed |
| WO-2009118106-A1 | DECORATIVE COSMETIC COMPOSITIONS | BAYER MATERIALSCIENCE AG (DE) | 2009-10-01 | — | — | WO | disclosed |
| EP-0010063-B1 | PROCESS FOR THE PREPARATION OF FURANYL-BENZAZOLES | CIBA-GEIGY AG (CH) | 1982-12-29 | — | — | EP | disclosed |
| EP-0010063-B1 | PROCESS FOR THE PREPARATION OF FURANYL-BENZAZOLES | CIBA-GEIGY AG (CH) | 1982-12-29 | — | — | EP | disclosed |
| EP-0010063-A2 | Process for the preparation of furanyl-benzazoles | CIBA-GEIGY AG (CH) | 1980-04-16 | — | — | EP | disclosed |
| EP-0010063-A2 | Process for the preparation of furanyl-benzazoles | CIBA-GEIGY AG (CH) | 1980-04-16 | — | — | EP | disclosed |
| EP-0010063-A2 | Process for the preparation of furanyl-benzazoles | CIBA-GEIGY AG (CH) | 1980-04-16 | — | — | EP | disclosed |