Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | SRC | P12931 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 2/20 | 0.40 |
| ▸ | CES1 | P23141 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8407965 | 1.00 | LMNA (0.44) | LMNAMAPK1SRCCYP2D6CES2 | |
| SCHEMBL21723253 | 0.98 | LMNA (0.46) | LMNAMAPK1SRCCYP2D6CES2 | |
| SCHEMBL15941285 | 0.98 | LMNA (0.46) | LMNAMAPK1SRCCYP2D6CES2 | |
| SCHEMBL6421419 | 0.98 | LMNA (0.46) | LMNAMAPK1SRCCYP2D6CES2 | |
| SCHEMBL9036 | 0.98 | LMNA (0.46) | LMNAMAPK1SRCCYP2D6CES2 | |
| Benzene SCHEMBL23120173 | 0.98 | LMNA (0.46) | LMNAMAPK1SRCCYP2D6CES2 | |
| SCHEMBL22470066 | 0.95 | LMNA (0.44) | LMNAMAPK1SRCCYP2D6CES2 | |
| Hydrochloric Acid SCHEMBL22230828 | 0.95 | LMNA (0.44) | LMNAMAPK1SRCCYP2D6CES2 | |
| SCHEMBL20723592 | 0.95 | LMNA (0.44) | LMNAMAPK1SRCCYP2D6CES2 | |
| SCHEMBL430932 | 0.95 | LMNA (0.44) | LMNAMAPK1SRCCYP2D6CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5993731-A | SINTERING A COMPACT CONTAINING PARTICLES CONSISTING OF A METAL AND CHEMICALLY-BOUND OXYGEN IN A REDUCING ATMOSPHERE, FORMING A METAL/METAL OXIDE EUTECTIC | BRUSH WELLMAN, INC. (US) | 1999-11-30 | — | — | US | disclosed |