Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.60 |
| ▸ | MMP2 | P08253 | 1/20 | 0.60 |
| ▸ | MMP9 | P14780 | 1/20 | 0.60 |
| ▸ | MMP8 | P22894 | 1/20 | 0.60 |
| ▸ | MMP13 | P45452 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 8/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.47 |
| ▸ | RELA | Q04206 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4784061 | 0.92 | MMP13 (0.63) | APPMMP2MMP9MMP8MMP13 | |
| SCHEMBL8396940 | 0.88 | APP (0.72) | APPMMP2MMP9MMP8MMP13 | |
| SCHEMBL2243418 | 0.82 | MMP13 (0.63) | APPMMP2MMP9MMP8MMP13 | |
| SCHEMBL1982194 | 0.78 | APP (0.64) | APPMMP2MMP9MMP8MMP13 | |
| SCHEMBL8433475 | 0.78 | APP (0.76) | APPMMP2MMP9MMP8MMP13 | |
| SCHEMBL12980741 | 0.78 | SMN1; SMN2 (0.65) | MMP2MMP9MMP8MMP13MAPT | |
| SCHEMBL12422162 | 0.77 | MMP13 (0.63) | APPMMP2MMP9MMP8MMP13 | |
| SCHEMBL2248504 | 0.77 | APP (0.52) | APPMMP2MMP9MMP8MMP13 | |
| SCHEMBL13178577 | 0.77 | APP (0.67) | APPMMP2MMP9MMP8MMP13 | |
| SCHEMBL8535715 | 0.77 | APP (0.55) | APPMMP2MMP9MMP8MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0721336-B1 | BENZAZOLE COMPOUNDS FOR USE IN THERAPY | CANCER RES CAMPAIGN TECH (GB) | 1999-07-14 | — | — | EP | disclosed |