Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 2/20 | 0.51 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.51 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.46 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.44 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.43 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7670648 | 0.88 | CHRNB2 (0.53) | CHRNB2CHRNA4TRPM8RIPK1NR1H2 | |
| SCHEMBL7658401 | 0.85 | CHRNB2 (0.53) | CHRNB2CHRNA4RIPK1NR1H2NR1H3 | |
| SCHEMBL8405283 | 0.83 | CHRNB2 (0.46) | CHRNB2CHRNA4TRPM8RIPK1HTT | |
| SCHEMBL7669732 | 0.77 | CHRNB2 (0.47) | CHRNB2CHRNA4TRPM8RIPK1NR1H2 | |
| SCHEMBL7668729 | 0.77 | KMT2A (0.48) | CHRNB2CHRNA4HTTSMN1; SMN2LMNA | |
| SCHEMBL10518385 | 0.75 | TDP1 (0.48) | CHRNB2CHRNA4TRPM8RIPK1HTT | |
| SCHEMBL7664882 | 0.75 | CHRNB2 (0.48) | CHRNB2CHRNA4RIPK1HTTSMN1; SMN2 | |
| SCHEMBL10512387 | 0.74 | CHRNB2 (0.49) | CHRNB2CHRNA4RIPK1NR1H2NR1H3 | |
| SCHEMBL7658397 | 0.74 | CHRNB2 (0.49) | CHRNB2CHRNA4RIPK1NR1H2NR1H3 | |
| SCHEMBL20057648 | 0.74 | CHRNB2 (0.60) | CHRNB2CHRNA4TRPM8RIPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5935981-A | INSECTICIDAL/MITICIDAL ACTIVITY | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-08-10 | — | — | US | disclosed |