Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 2/20 | 0.46 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7658397 | 0.87 | CHRNB2 (0.49) | CHRNB2CHRNA4SMN1; SMN2HTTTDP1 | |
| SCHEMBL10512387 | 0.87 | CHRNB2 (0.49) | CHRNB2CHRNA4SMN1; SMN2HTTTDP1 | |
| SCHEMBL7662013 | 0.85 | CHRNB2 (0.47) | CHRNB2CHRNA4SMN1; SMN2HTTALDH1A1 | |
| SCHEMBL8405284 | 0.83 | CHRNB2 (0.51) | CHRNB2CHRNA4SMN1; SMN2HTTTDP1 | |
| SCHEMBL7669729 | 0.82 | CHRNB2 (0.43) | CHRNB2CHRNA4SMN1; SMN2HTTTDP1 | |
| SCHEMBL7670898 | 0.81 | SMN1; SMN2 (0.45) | CHRNB2CHRNA4SMN1; SMN2HTTL3MBTL1 | |
| SCHEMBL7664877 | 0.80 | KMT2A (0.46) | CHRNB2CHRNA4SMN1; SMN2HTTTDP1 | |
| SCHEMBL7668724 | 0.80 | SMN1; SMN2 (0.51) | CHRNB2CHRNA4SMN1; SMN2HTTALDH1A1 | |
| SCHEMBL7670648 | 0.79 | CHRNB2 (0.53) | CHRNB2CHRNA4SMN1; SMN2HTTTDP1 | |
| SCHEMBL7662170 | 0.78 | LMNA (0.42) | CHRNB2CHRNA4SMN1; SMN2HTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5935981-A | INSECTICIDAL/MITICIDAL ACTIVITY | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-08-10 | — | — | US | disclosed |