SCHEMBL8405288

SCHEMBL8405288

C=Cc1ccc(/C=N/c2ccccc2)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.58
L3MBTL1 Q9Y468 5/20 0.58
KDM4E B2RXH2 3/20 0.58
GLA P06280 1/20 0.58
PTGS2 P35354 2/20 0.55
PTGS1 P23219 1/20 0.55
TSHR P16473 1/20 0.54
MEN1 O00255 5/20 0.49
KMT2A Q03164 5/20 0.49
CA2 P00918 6/20 0.48
CA1 P00915 5/20 0.48
S100B P04271 1/20 0.47
CA9 Q16790 3/20 0.46
CA12 O43570 1/20 0.46
MAPT P10636 4/20 0.44
THRB P10828 3/20 0.44
MAPK1 P28482 2/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
TP53 P04637 1/20 0.44
ALOX15 P16050 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8405291 1.00 ALDH1A1 (0.58) ALDH1A1L3MBTL1KDM4EGLAPTGS2
SCHEMBL18537896 0.94 ALDH1A1 (0.58) ALDH1A1L3MBTL1KDM4EGLAPTGS2
SCHEMBL1101311 0.89 ALDH1A1 (0.55) ALDH1A1L3MBTL1KDM4EGLAPTGS2
SCHEMBL1101313 0.89 ALDH1A1 (0.55) ALDH1A1L3MBTL1KDM4EGLAPTGS2
SCHEMBL14129042 0.89 ALDH1A1 (0.69) ALDH1A1L3MBTL1KDM4EGLAPTGS2
SCHEMBL59999 0.84 ALDH1A1 (0.63) ALDH1A1L3MBTL1KDM4EGLAPTGS2
SCHEMBL60000 0.84 ALDH1A1 (0.63) ALDH1A1L3MBTL1KDM4EGLAPTGS2
SCHEMBL13084384 0.84 ALDH1A1 (0.63) ALDH1A1L3MBTL1KDM4EGLAPTGS2
SCHEMBL1374708 0.81 ALDH1A1 (0.61) ALDH1A1L3MBTL1KDM4EGLAPTGS2
SCHEMBL340770 0.81 ALDH1A1 (0.61) ALDH1A1L3MBTL1KDM4EGLAPTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-9255646-A None JP disclosed
WO-2023199058-A1 ANTIMICROBIAL POROUS FRAMEWORKS THE UNIVERSITY OF BRISTOL (GB) 2023-10-19 WO disclosed
US-5985012-A SELF-POLISHING PAINT COMPRISING ANTIFOULING AGENT AND RESIN VEHICLE COMPRISING VINYL POLYMER HAVING PRIMARY AMINE PENDANT GROUPS BOUND BY REACTION WITH PENDANT CARBONYL GROUPS NIPPON PAINT CO., LTD. (JP) 1999-11-16 US disclosed
EP-0849290-A1 RESIN CONTAINING AMINE BONDED THERETO AND ANTIFOULING PAINT Nippon Paint Co., Ltd. (JP) 1998-06-24 EP disclosed
JP-H09255646-A VINYL MONOMER HAVING AZOMETHINE STRUCTURE NIPPON PAINT CO LTD 1997-09-30 JP disclosed