Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.69 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.69 |
| ▸ | GLA | P06280 | 1/20 | 0.69 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.64 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.64 |
| ▸ | CA2 | P00918 | 6/20 | 0.57 |
| ▸ | CA1 | P00915 | 5/20 | 0.57 |
| ▸ | S100B | P04271 | 2/20 | 0.55 |
| ▸ | CA9 | Q16790 | 3/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | THRB | P10828 | 3/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL59999 | 0.94 | ALDH1A1 (0.63) | ALDH1A1L3MBTL1KDM4EGLAPTGS2 | |
| SCHEMBL60000 | 0.94 | ALDH1A1 (0.63) | ALDH1A1L3MBTL1KDM4EGLAPTGS2 | |
| SCHEMBL13084384 | 0.94 | ALDH1A1 (0.63) | ALDH1A1L3MBTL1KDM4EGLAPTGS2 | |
| Water SCHEMBL15846002 | 0.92 | ALDH1A1 (0.61) | ALDH1A1L3MBTL1KDM4EGLAPTGS2 | |
| SCHEMBL22577661 | 0.92 | ALDH1A1 (0.61) | ALDH1A1L3MBTL1KDM4EGLAPTGS2 | |
| SCHEMBL1374708 | 0.92 | ALDH1A1 (0.61) | ALDH1A1L3MBTL1KDM4EGLAPTGS2 | |
| SCHEMBL9685935 | 0.92 | ALDH1A1 (0.61) | ALDH1A1L3MBTL1KDM4EGLAPTGS2 | |
| Ammonia Solution, Strong SCHEMBL2273341 | 0.92 | ALDH1A1 (0.61) | ALDH1A1L3MBTL1KDM4EGLAPTGS2 | |
| SCHEMBL340770 | 0.92 | ALDH1A1 (0.61) | ALDH1A1L3MBTL1KDM4EGLAPTGS2 | |
| SCHEMBL28312209 | 0.92 | ALDH1A1 (0.61) | ALDH1A1L3MBTL1KDM4EGLAPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120302720-A1 | Novel Polyazomethine | SOKEN CHEMICAL & ENGINEERING CO., LTD. (JP) | 2012-11-29 | — | — | US | disclosed |
| US-7355075-B2 | Reacting a compound of a hydroxyl functionality, a carbonyl functionality, or both a hydroxyl functionality and a carbonyl functionality with reactant having an amine functionality in the presence of ordered porous manganese-based octahedral molecular sieves and an oxygen gas | THE UNIVERSITY OF CONNECTICUT (US) | 2008-04-08 | — | — | US | disclosed |
| US-7355075-B2 | Reacting a compound of a hydroxyl functionality, a carbonyl functionality, or both a hydroxyl functionality and a carbonyl functionality with reactant having an amine functionality in the presence of ordered porous manganese-based octahedral molecular sieves and an oxygen gas | THE UNIVERSITY OF CONNECTICUT (US) | 2008-04-08 | — | — | US | disclosed |
| US-20070027344-A1 | METHOD OF PRODUCING IMINES | THE UNIVERSITY OF CONNECTICUT (US) | 2007-02-01 | — | — | US | disclosed |
| US-20070027344-A1 | METHOD OF PRODUCING IMINES | THE UNIVERSITY OF CONNECTICUT (US) | 2007-02-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070027344-A1 | METHOD OF PRODUCING IMINES | MT-CO2, INMT, SCO2 | ALDH1A1 1989/4885L3MBTL1 4357/4885KDM4E 2592/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.