Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.31 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.30 |
| ▸ | PTGES | O14684 | 1/20 | 0.30 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.30 |
| ▸ | STAT3 | P40763 | 1/20 | 0.30 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8405404 | 0.89 | HTT (0.41) | HTTPTGS1PTGESALOX5STAT3 | |
| SCHEMBL8067294 | 0.89 | HTT (0.44) | HTTPTGS1PTGS2MCL1ALOX5 | |
| SCHEMBL8409231 | 0.84 | ALDH1A1 (0.31) | PTGS1PTGS2PTGESALOX5STAT3 | |
| SCHEMBL8405762 | 0.83 | HTT (0.37) | HTTMCL1 | |
| SCHEMBL7075218 | 0.83 | HTT (0.40) | HTTPTGS1PTGS2MCL1 | |
| SCHEMBL8405655 | 0.82 | HTT (0.40) | HTTPTGS1PTGESALOX5STAT3 | |
| SCHEMBL8408852 | 0.81 | HTT (0.36) | HTTPTGS1PTGESALOX5STAT3 | |
| SCHEMBL8408672 | 0.81 | HTT (0.39) | HTTPTGS1PTGS2MCL1ALOX5 | |
| SCHEMBL8409086 | 0.81 | GSR (0.37) | HTT | |
| SCHEMBL8408830 | 0.80 | HTT (0.41) | HTTPTGS1PTGS2MCL1ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5872137-A | AROMATIC OXY DIHALOPRENE COMPOUNDS INSECTICIDAL/ACARICIDAL AGENTS CONTAINING SAME, AND INTERMEDIATES FOR THEIR PRODUCTION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1999-02-16 | — | — | US | disclosed |
| EP-0722430-B1 | DIHALOPROPENE COMPOUNDS, INSECTICIDAL/ACARICIDAL AGENTS CONTAINING SAME, AND INTERMEDIATES FOR THEIR PRODUCTION | SUMITOMO CHEMICAL CO (JP) | 1998-10-21 | — | — | EP | disclosed |