Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.31 |
| ▸ | PTGES | O14684 | 1/20 | 0.30 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.30 |
| ▸ | STAT3 | P40763 | 1/20 | 0.30 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7979194 | 0.89 | PTGS1 (0.37) | ALDH1A1PTGS1PTGS2ALOX5 | |
| SCHEMBL8408843 | 0.89 | MAOB (0.32) | PTGS1PTGESALOX5STAT3NFE2L2 | |
| SCHEMBL8405332 | 0.84 | HTT (0.39) | PTGS1PTGS2PTGESALOX5STAT3 | |
| SCHEMBL8407153 | 0.83 | PTGS2 (0.33) | ALDH1A1PTGS1PTGS2ALOX5 | |
| SCHEMBL8405435 | 0.83 | PTGES (0.31) | PTGS1PTGESALOX5STAT3NFE2L2 | |
| SCHEMBL8405553 | 0.82 | ALOX5 (0.34) | ALDH1A1PTGS1PTGESALOX5STAT3 | |
| SCHEMBL8409279 | 0.81 | MCL1 (0.33) | — | |
| SCHEMBL7981782 | 0.81 | MCL1 (0.33) | PTGS1PTGS2 | |
| SCHEMBL8405660 | 0.81 | GSR (0.41) | — | |
| SCHEMBL8405440 | 0.80 | ALDH1A1 (0.33) | ALDH1A1PTGS1PTGS2ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5872137-A | AROMATIC OXY DIHALOPRENE COMPOUNDS INSECTICIDAL/ACARICIDAL AGENTS CONTAINING SAME, AND INTERMEDIATES FOR THEIR PRODUCTION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1999-02-16 | — | — | US | disclosed |
| EP-0722430-B1 | DIHALOPROPENE COMPOUNDS, INSECTICIDAL/ACARICIDAL AGENTS CONTAINING SAME, AND INTERMEDIATES FOR THEIR PRODUCTION | SUMITOMO CHEMICAL CO (JP) | 1998-10-21 | — | — | EP | disclosed |
| EP-0722430-A1 | DIHALOPROPENE COMPOUNDS, INSECTICIDAL/ACARICIDAL AGENTS CONTAINING SAME, AND INTERMEDIATES FOR THEIR PRODUCTION | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-07-24 | — | — | EP | disclosed |
| WO-1996004228-A1 | DIHALOPROPENE COMPOUNDS, INSECTICIDAL/ACARICIDAL AGENTS CONTAINING SAME, AND INTERMEDIATES FOR THEIR PRODUCTION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1996-02-15 | — | — | WO | disclosed |