SCHEMBL8405474

SCHEMBL8405474

CC(C)(C)c1ccc(Oc2cccc(COc3c(Cl)cc(O)cc3Cl)c2)cc1

nearest known ligand 0.44

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
NR4A1 P22736 1/20 0.43
NR4A2 P43354 1/20 0.43
NR4A3 Q92570 1/20 0.43
FFAR1 O14842 7/20 0.42
FFAR4 Q5NUL3 1/20 0.42
FAAH O00519 1/20 0.41
FDFT1 P37268 1/20 0.41
PKM P14618 1/20 0.39
MAOB P27338 1/20 0.38
HSP90AA1 P07900 1/20 0.38
APP P05067 1/20 0.38
EPOR P19235 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8408975 0.86 FFAR1 (0.55) FFAR1FFAR4MAOB
SCHEMBL8405973 0.86 PPARG (0.47) NR4A2FFAR1FFAR4MAOB
SCHEMBL8405485 0.86 FFAR1 (0.51) FFAR1FFAR4
SCHEMBL8657689 0.85 FFAR1 (0.38) NR4A1NR4A2NR4A3FFAR1FFAR4
SCHEMBL8408818 0.84 FFAR1 (0.44) NR4A2FFAR1FFAR4FAAHPKM
SCHEMBL8409040 0.83 HSP90AA1 (0.54) FFAR1FFAR4FAAHFDFT1MAOB
SCHEMBL8405946 0.81 RXRA (0.50) NR4A1NR4A2NR4A3MAOBAPP
SCHEMBL8409016 0.81 MRGPRX4 (0.47) NR4A2FFAR1FFAR4FAAHFDFT1
SCHEMBL8405447 0.79 MAOB (0.54) MAOB
SCHEMBL8405445 0.77 FFAR1 (0.49) NR4A2FFAR1FFAR4MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5872137-A AROMATIC OXY DIHALOPRENE COMPOUNDS INSECTICIDAL/ACARICIDAL AGENTS CONTAINING SAME, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-02-16 US disclosed
EP-0722430-B1 DIHALOPROPENE COMPOUNDS, INSECTICIDAL/ACARICIDAL AGENTS CONTAINING SAME, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL CO (JP) 1998-10-21 EP disclosed
EP-0722430-A1 DIHALOPROPENE COMPOUNDS, INSECTICIDAL/ACARICIDAL AGENTS CONTAINING SAME, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1996-07-24 EP disclosed
WO-1996004228-A1 DIHALOPROPENE COMPOUNDS, INSECTICIDAL/ACARICIDAL AGENTS CONTAINING SAME, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-02-15 WO disclosed