Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.67 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.49 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.49 |
| ▸ | DHODH | Q02127 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6436959 | 0.94 | LMNA (0.63) | LMNAALDH1A1HIF1AHDAC1HDAC6 | |
| SCHEMBL2439695 | 0.90 | ALDH1A1 (0.76) | LMNAALDH1A1HIF1ASLC6A3KDM4E | |
| SCHEMBL10411824 | 0.87 | ALDH1A1 (0.67) | LMNAALDH1A1HIF1ADHODHKDM4E | |
| SCHEMBL10360804 | 0.84 | ALDH1A1 (0.77) | LMNAALDH1A1HIF1ASLC6A3KDM4E | |
| SCHEMBL383349 | 0.83 | ALDH1A1 (0.66) | LMNAALDH1A1HIF1ASLC6A3DHODH | |
| SCHEMBL1789262 | 0.83 | ALDH1A1 (0.66) | LMNAALDH1A1HIF1AMAPK1SMN1; SMN2 | |
| SCHEMBL5734169 | 0.82 | ALDH1A1 (0.64) | LMNAALDH1A1HIF1ADHODHKDM4E | |
| SCHEMBL385826 | 0.82 | ALDH1A1 (0.64) | LMNAALDH1A1HIF1ASMN1; SMN2DHODH | |
| SCHEMBL6621914 | 0.82 | ALDH1A1 (0.64) | LMNAALDH1A1HIF1ASLC6A3DHODH | |
| SCHEMBL28106654 | 0.82 | ALDH1A1 (0.64) | LMNAALDH1A1MAPK1SMN1; SMN2DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0927192-A1 | MODIFIED AMINOACIDS, PHARMACEUTICALS CONTAINING THESE COMPOUNDS AND METHOD FOR THEIR PRODUCTION | Dr. Karl Thomae GmbH (DE) | 1999-07-07 | — | — | EP | disclosed |
| WO-1998011128-A1 | MODIFIED AMINOACIDS, PHARMACEUTICALS CONTAINING THESE COMPOUNDS AND METHOD FOR THEIR PRODUCTION | DR. KARL THOMAE GMBH (DE) | 1998-03-19 | — | — | WO | disclosed |