Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 4/20 | 0.52 |
| ▸ | ADRA2C | P18825 | 4/20 | 0.52 |
| ▸ | ADRA1D | P25100 | 4/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.52 |
| ▸ | ADRA1B | P35368 | 4/20 | 0.52 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.52 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fumaric Acid SCHEMBL8901722 | 0.90 | ADRA2A (0.44) | ADRA2AADRA2CADRA1DADRA1AADRA1B | |
| SCHEMBL6976306 | 0.89 | ADRA2A (0.40) | ADRA2AADRA2CADRA1DADRA1AADRA1B | |
| SCHEMBL8403307 | 0.83 | ADRA2A (0.34) | ADRA2AADRA2CADRA1DADRA1AADRA1B | |
| SCHEMBL8403326 | 0.80 | ADRA2A (0.33) | ADRA2AADRA2CADRA1DADRA1AADRA1B | |
| SCHEMBL6968286 | 0.68 | MAPT (0.38) | ALDH1A1HTTMAPT | |
| SCHEMBL7206673 | 0.68 | ADRA2A (0.34) | ADRA2AADRA2CADRA1DADRA1AADRA1B | |
| SCHEMBL8020018 | 0.67 | ADRA2B (0.41) | ADRA2AADRA2CADRA1DADRA1AADRA1B | |
| SCHEMBL7808630 | 0.67 | ADRA2A (1.00) | ADRA2AADRA2CADRA1DADRA1AADRA1B | |
| SCHEMBL7202843 | 0.67 | — | — | |
| Hydrochloric Acid SCHEMBL6977245 | 0.67 | MAPT (0.37) | ALDH1A1HTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5965595-A | SIDE EFFECT REDUCTION; TREATING NASAL CONGESTION AND OTHER ALPHA-2 ADRENORECEPTOR MODULATED DISORDERS, WILL NOT CAUSE HYPERTENSION | THE PROCTER & GAMBLE COMPANY (US) | 1999-10-12 | — | — | US | disclosed |
| US-5914342-A | 2-imidazolinylamino heterocyclic compounds useful as alpha-2 adrenoceptor agonists | THE PROCTER & GAMBLE COMPANY (US) | 1999-06-22 | — | — | US | disclosed |
| US-5663189-A | RESPIRATORY, EYES, GASTROINTESTINAL | THE PROCTER & GAMBLE COMPANY (US) | 1997-09-02 | — | — | US | disclosed |