Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.59 |
| ▸ | RAB9A | P51151 | 3/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.47 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.47 |
| ▸ | CTSS | P25774 | 7/20 | 0.45 |
| ▸ | CTSL | P07711 | 6/20 | 0.45 |
| ▸ | CTSB | P07858 | 4/20 | 0.45 |
| ▸ | CTSK | P43235 | 2/20 | 0.45 |
| ▸ | PGR | P06401 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6841168 | 0.84 | NPC1 (0.64) | NPC1RAB9ASMN1; SMN2LMNAMAPT | |
| SCHEMBL6183994 | 0.81 | CTSS (0.72) | CTSSCTSLCTSBCTSK | |
| SCHEMBL13564630 | 0.80 | NPC1 (0.68) | NPC1RAB9ASMN1; SMN2LMNAMAPT | |
| SCHEMBL7345056 | 0.80 | SMN1; SMN2 (0.59) | NPC1RAB9ASMN1; SMN2LMNAMAPT | |
| SCHEMBL7401301 | 0.79 | NPC1 (0.67) | NPC1RAB9ASMN1; SMN2LMNAMAPT | |
| SCHEMBL23585702 | 0.79 | SMN1; SMN2 (0.58) | NPC1RAB9ASMN1; SMN2LMNAMAPT | |
| SCHEMBL20523875 | 0.78 | SMN1; SMN2 (0.52) | NPC1RAB9ASMN1; SMN2LMNAMAPT | |
| SCHEMBL854096 | 0.77 | CTSS (0.68) | SMN1; SMN2LMNACTSSCTSLCTSB | |
| SCHEMBL16078292 | 0.77 | SMN1; SMN2 (0.68) | NPC1RAB9ASMN1; SMN2LMNAMAPT | |
| SCHEMBL15637509 | 0.77 | NPC1 (0.62) | NPC1RAB9ASMN1; SMN2LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5883260-A | Process for producing 1-substituted-hydantoins | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1999-03-16 | — | — | US | disclosed |