Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 13/20 | 0.68 |
| ▸ | CTSL | P07711 | 11/20 | 0.68 |
| ▸ | CTSB | P07858 | 7/20 | 0.68 |
| ▸ | CTSK | P43235 | 3/20 | 0.68 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1606573 | 0.85 | LMNA (0.61) | CTSSCTSLCTSBCTSKLMNA | |
| SCHEMBL2391033 | 0.84 | LMNA (0.65) | CTSSCTSLCTSBCTSKLMNA | |
| SCHEMBL5532541 | 0.84 | CTSS (0.62) | CTSSCTSLCTSBCTSKLMNA | |
| SCHEMBL3211861 | 0.83 | LMNA (0.59) | CTSSCTSLCTSBCTSKLMNA | |
| SCHEMBL6185607 | 0.83 | CTSS (0.60) | CTSSCTSLCTSBCTSKLMNA | |
| SCHEMBL6183076 | 0.83 | HTT (0.60) | CTSSCTSLCTSBCTSKLMNA | |
| SCHEMBL6048184 | 0.83 | CTSS (0.61) | CTSSCTSLCTSBCTSKLMNA | |
| SCHEMBL5532252 | 0.82 | CTSS (0.60) | CTSSCTSLCTSBCTSKLMNA | |
| Benzyl Phenethylcarbamate SCHEMBL27338403 | 0.81 | LMNA (0.61) | CTSSCTSLCTSBCTSKLMNA | |
| SCHEMBL12176970 | 0.81 | HTT (0.67) | CTSSCTSLCTSBCTSKLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 120 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1934561-B1 | IMPROVED TIME/TEMPERATURE INDICATORS | SUN CHEMICAL CORP (US) | 2018-11-07 | — | — | EP | claimed |
| US-20080269050-A1 | Time/Temperature Indicators | SUN CHEMICAL CORPORATION (US) | 2008-10-30 | — | — | US | claimed |
| EP-1934561-A1 | IMPROVED TIME/TEMPERATURE INDICATORS | Sun Chemical Corporation (US) | 2008-06-25 | — | — | EP | claimed |
| WO-2007035365-A1 | IMPROVED TIME/TEMPERATURE INDICATORS | SUN CHEMICAL CORPORATION (US) | 2007-03-29 | — | — | WO | claimed |
| WO-2006091464-A1 | IMPROVED TIME/ TEMPERATURE INDICATORS | SUN CHEMICAL CORPORATION (US) | 2006-08-31 | — | — | WO | claimed |
| WO-2006091465-A1 | TIME/TEMPERATURE INDICATORS, THEIR PREPARATION AND USE | SUN CHEMICAL CORPORATION (US) | 2006-08-31 | — | — | WO | claimed |
| US-20240043436-A1 | METHODS AND COMPOUNDS FOR RESTORING MUTANT p53 FUNCTION | PMV PHARMACEUTICALS, INC. | 2024-02-08 | — | — | US | disclosed |
| US-11851425-B2 | Combination treatments comprising administration of 1H-pyrazolo[4,3-B]pyridines | H. LUNDBECK A/S (DK) | 2023-12-26 | — | — | US | disclosed |
| US-11807644-B2 | Methods and compounds for restoring mutant p53 function | PMV PHARMACEUTICALS, INC. (US) | 2023-11-07 | — | — | US | disclosed |
| US-11634416-B2 | Combination treatments comprising administration of 1H-pyrazolo[4,3-b]pyridines | H. LUNDBECK A/S (DK) | 2023-04-25 | — | — | US | disclosed |
| EP-4149459-A1 | METHODS AND COMPOUNDS FOR RESTORING MUTANT P53 FUNCTION | PMV Pharmaceuticals, Inc. (US) | 2023-03-22 | — | — | EP | disclosed |
| US-20230002403-A1 | METHODS AND COMPOUNDS FOR RESTORING MUTANT p53 FUNCTION | PMV PHARMACEUTICALS, INC. | 2023-01-05 | — | — | US | disclosed |
| CN-110099901-B | Pyrazolo [3,4-b ] pyridines and imidazo [1,5-b ] pyridazines as PDE1 inhibitors | H.隆德贝克有限公司 | 2023-01-03 | — | — | CN | disclosed |
| WO-1997045403-A1 | ARYL SUBSTITUTED CYCLIC AMINES AS SELECTIVE DOPAMINE D3 LIGANDS | PHARMACIA & UPJOHN COMPANY (US) | 1997-12-04 | — | — | WO | disclosed |
| US-5629285-A | Inhibitors of TNF-α secretion | IMMUNEX CORPORATION (US) | 1997-05-13 | — | — | US | disclosed |
| EP-0715619-A4 | INHIBITORS OF TNF-ALPHA SECRETION | IMMUNEX CORP (US) | 1997-03-19 | — | — | EP | disclosed |
| US-5594106-A | Inhibitors of TNF-α secretion | IMMUNEX CORPORATION (US) | 1997-01-14 | — | — | US | disclosed |
| EP-0715619-A1 | INHIBITORS OF TNF-ALPHA SECRETION | IMMUNEX CORPORATION (US) | 1996-06-12 | — | — | EP | disclosed |
| WO-1995006031-A1 | INHIBITORS OF TNF-ALPHA SECRETION | IMMUNEX CORPORATION (US) | 1995-03-02 | — | — | WO | disclosed |
| EP-0201999-A1 | Substituted 2-cyano-2-oximino-acetamides, processes for their production and their use as fungicides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1986-11-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230002403-A1 | METHODS AND COMPOUNDS FOR RESTORING MUTANT p53 FUNCTION | TP53, TP53BP1, HRAS | CTSS 3253/4885CTSL 2966/4885CTSB 3022/4885 |
| US-11851425-B2 | Combination treatments comprising administration of 1H-pyrazolo[4,3-B]pyridines | PDE3B, PDE1B, PDE12 | CTSS 1996/4885CTSL 3166/4885CTSB 896/4885 |
| US-11634416-B2 | Combination treatments comprising administration of 1H-pyrazolo[4,3-b]pyridines | PDE1B, PDE3B, PDE1A | CTSS 1985/4885CTSL 2791/4885CTSB 1206/4885 |
| US-11807644-B2 | Methods and compounds for restoring mutant p53 function | TP53, TP53BP1, HRAS | CTSS 3253/4885CTSL 2966/4885CTSB 3022/4885 |
| US-20240043436-A1 | METHODS AND COMPOUNDS FOR RESTORING MUTANT p53 FUNCTION | TP53, TP53BP1, HRAS | CTSS 3253/4885CTSL 2966/4885CTSB 3022/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.