Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 1/20 | 0.34 |
| ▸ | PLAU | P00749 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8409038 | 0.95 | PLAU (0.33) | PDK2PLAUKDM4EMAPK1SMN1; SMN2 | |
| SCHEMBL8561642 | 0.91 | PDK2 (0.34) | PDK2 | |
| SCHEMBL8409895 | 0.91 | KDM4E (0.41) | PDK2KDM4ETP53MAPK1SMN1; SMN2 | |
| SCHEMBL8408646 | 0.90 | PLAU (0.33) | PLAUKDM4EMAPK1THRB | |
| SCHEMBL8408474 | 0.88 | L3MBTL1 (0.34) | PDK2KDM4ETHRB | |
| SCHEMBL8408467 | 0.88 | PLAU (0.35) | PLAUKDM4ETHRB | |
| SCHEMBL8407424 | 0.88 | PLAU (0.33) | PLAUKDM4EMAPK1 | |
| SCHEMBL8409045 | 0.87 | KDM4E (0.39) | KDM4ETHRBSMN1; SMN2 | |
| SCHEMBL8405821 | 0.87 | THRB (0.33) | PDK2THRB | |
| SCHEMBL7981958 | 0.87 | PLAU (0.40) | PLAUKDM4ETHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5872137-A | AROMATIC OXY DIHALOPRENE COMPOUNDS INSECTICIDAL/ACARICIDAL AGENTS CONTAINING SAME, AND INTERMEDIATES FOR THEIR PRODUCTION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1999-02-16 | — | — | US | disclosed |
| EP-0722430-B1 | DIHALOPROPENE COMPOUNDS, INSECTICIDAL/ACARICIDAL AGENTS CONTAINING SAME, AND INTERMEDIATES FOR THEIR PRODUCTION | SUMITOMO CHEMICAL CO (JP) | 1998-10-21 | — | — | EP | disclosed |