Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 7/20 | 0.56 |
| ▸ | CTSS | P25774 | 7/20 | 0.56 |
| ▸ | CTSK | P43235 | 7/20 | 0.56 |
| ▸ | MMP1 | P03956 | 2/20 | 0.56 |
| ▸ | MMP2 | P08253 | 2/20 | 0.56 |
| ▸ | MMP3 | P08254 | 2/20 | 0.56 |
| ▸ | MMP7 | P09237 | 2/20 | 0.56 |
| ▸ | MMP9 | P14780 | 2/20 | 0.56 |
| ▸ | MMP13 | P45452 | 2/20 | 0.56 |
| ▸ | LARS1 | Q9P2J5 | 1/20 | 0.54 |
| ▸ | ADAMTS4 | O75173 | 3/20 | 0.50 |
| ▸ | CTSB | P07858 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5191083 | 0.88 | MMP2 (0.70) | CTSLCTSSCTSKMMP1MMP2 | |
| SCHEMBL15251807 | 0.88 | MMP2 (0.70) | CTSLCTSSCTSKMMP1MMP2 | |
| SCHEMBL6561338 | 0.88 | MMP2 (0.70) | CTSLCTSSCTSKMMP1MMP2 | |
| SCHEMBL16388801 | 0.86 | CTSL (0.57) | CTSLCTSSCTSKMMP1MMP2 | |
| SCHEMBL31086879 | 0.85 | CTSL (0.62) | CTSLCTSSCTSKMMP1MMP2 | |
| SCHEMBL17789291 | 0.82 | CTSL (0.54) | CTSLCTSSCTSKMMP1MMP2 | |
| SCHEMBL31086926 | 0.81 | MMP2 (0.82) | MMP1MMP2MMP3MMP7MMP9 | |
| SCHEMBL21067512 | 0.81 | MMP2 (0.82) | MMP1MMP2MMP3MMP7MMP9 | |
| SCHEMBL21067511 | 0.81 | MMP2 (0.82) | MMP1MMP2MMP3MMP7MMP9 | |
| SCHEMBL19450360 | 0.80 | MMP2 (0.67) | CTSLCTSSCTSKMMP1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0925786-A1 | REMEDIES FOR ISCHEMIC DISEASES | MITSUBISHI CHEMICAL CORPORATION (JP) | 1999-06-30 | — | — | EP | disclosed |
| EP-0810221-A1 | OXYGEN-CONTAINING HETEROCYCLIC DERIVATIVES | MITSUBISHI CHEMICAL CORPORATION (JP) | 1997-12-03 | — | — | EP | disclosed |