Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19203370 | 0.74 | MEN1 (0.35) | — | |
| SCHEMBL19220449 | 0.70 | EED (0.35) | KCNH2 | |
| SCHEMBL2607624 | 0.70 | CA2 (0.41) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8406548 | 0.70 | — | — | |
| SCHEMBL19386439 | 0.68 | EED (0.33) | KCNH2 | |
| SCHEMBL7781715 | 0.68 | KMT2A (0.35) | — | |
| SCHEMBL31561735 | 0.67 | LMNA (0.37) | — | |
| SCHEMBL20858639 | 0.67 | KCNH2 (0.37) | KCNH2 | |
| SCHEMBL5988407 | 0.65 | HTR2A (0.44) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL15582364 | 0.65 | MEN1 (0.40) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0923567-A1 | BENZYLAMINE DERIVATIVES, THEIR PREPARATION AND THEIR APPLICATION IN THERAPEUTICS | SYNTHELABO (FR) | 1999-06-23 | — | — | EP | disclosed |
| WO-1998008834-A1 | BENZYLAMINE DERIVATIVES, THEIR PREPARATION AND THEIR APPLICATION IN THERAPEUTICS | SYNTHELABO (FR) | 1998-03-05 | — | — | WO | disclosed |