Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARA | P10276 | 1/20 | 0.53 |
| ▸ | RARB | P10826 | 1/20 | 0.53 |
| ▸ | FFAR4 | Q5NUL3 | 8/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 6/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.49 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.49 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.49 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.49 |
| ▸ | ALB | P02768 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8407566 | 0.86 | RARA (0.49) | RARARARBHDAC1HDAC2HDAC3 | |
| SCHEMBL8408075 | 0.86 | FFAR4 (0.47) | FFAR4FFAR1HDAC1HDAC2HDAC3 | |
| Hydrochloric Acid SCHEMBL8409943 | 0.80 | PRSS1 (0.69) | PPARAITGB3ITGA2BF2PLAU | |
| SCHEMBL8407255 | 0.79 | PRSS1 (0.68) | PPARAITGB3ITGA2BF2PLAU | |
| SCHEMBL5522432 | 0.76 | PRMT1 (0.75) | PPARAITGB3ITGA2BF2PLAU | |
| SCHEMBL14599520 | 0.76 | PRMT1 (0.75) | PPARAITGB3ITGA2BF2PLAU | |
| Pentamidine SCHEMBL21462087 | 0.76 | PRMT1 (0.75) | PPARAITGB3ITGA2BF2PLAU | |
| Hydrochloric Acid SCHEMBL5526299 | 0.75 | PRSS1 (0.76) | PPARAITGB3ITGA2BF2PLAU | |
| SCHEMBL8410366 | 0.75 | PRSS1 (0.65) | ITGB3ITGA2BF2PLAUPRMT1 | |
| SCHEMBL7610607 | 0.75 | RARB (0.83) | RARARARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5922763-A | ANTICOAGULANT; CARDIOVASCULAR DISORDERS | DR. KARL THOMAE GMBH (DE) | 1999-07-13 | — | — | US | disclosed |
| US-5736559-A | CARDIOVASCULAR DISORDERS; RESPIRATORY SYSTEM DISORDERS | KARL THOMAE GMBH (DE) | 1998-04-07 | — | — | US | disclosed |
| US-5597825-A | AGGREGATION INHIBITORS | DR. KARL THOMAE GMBH (DE) | 1997-01-28 | — | — | US | disclosed |
| EP-0496378-B1 | Biphenylderivatives, drugs containing these compounds and processes for their preparation | THOMAE GMBH DR K (DE) | 1995-09-20 | — | — | EP | disclosed |
| EP-0496378-A1 | Biphenylderivatives, drugs containing these compounds and processes for their preparation | Dr. Karl Thomae GmbH (DE) | 1992-07-29 | — | — | EP | disclosed |