Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | GLA | P06280 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.56 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29623480 | 1.00 | GPR84 (0.65) | GPR84ALDH1A1TSHRLMNAHPGD | |
| SCHEMBL9012524 | 0.88 | ALDH1A1 (0.63) | GPR84ALDH1A1TSHRLMNAHPGD | |
| SCHEMBL1615011 | 0.87 | TSHR (0.69) | GPR84ALDH1A1TSHRLMNAHPGD | |
| SCHEMBL24815224 | 0.86 | GPR84 (0.63) | GPR84ALDH1A1TSHRLMNASLC6A4 | |
| SCHEMBL30396876 | 0.86 | GPR84 (0.63) | GPR84LMNANPSR1SLC6A4MAPT | |
| SCHEMBL5228493 | 0.86 | GPR84 (0.63) | GPR84LMNANPSR1SLC6A4MAPT | |
| SCHEMBL29043861 | 0.85 | GPR84 (0.58) | GPR84ALDH1A1TSHRLMNAHPGD | |
| SCHEMBL16540415 | 0.84 | GPR84 (0.61) | GPR84TSHRHPGDSLC6A4NR4A2 | |
| SCHEMBL25139653 | 0.83 | GPR84 (0.59) | GPR84ALDH1A1TSHRLMNASLC6A4 | |
| SCHEMBL25139528 | 0.83 | GPR84 (0.59) | GPR84TSHRLMNASLC6A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 89 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115974758-B | Carboxymethyl ketone compound and preparation method thereof | 生物岛实验室 | 2025-06-10 | — | — | CN | claimed |
| CN-119332255-A | Electrochemical synthesis method of arundone derivatives | 云南师范大学 | 2025-01-21 | — | — | CN | claimed |
| CN-118086928-A | Method for electrochemical synthesis of pyrimidoindole derivative under mild condition | 湘潭大学 | 2024-05-28 | — | — | CN | claimed |
| CN-114933599-B | Double beta-carboline compound and medicinal salt, preparation method and application thereof | 中国人民解放军空军军医大学 | 2023-08-01 | — | — | CN | claimed |
| CN-115974758-A | Carboxymethyl ketone compound and preparation method thereof | 生物岛实验室 | 2023-04-18 | — | — | CN | claimed |
| CN-114933599-A | Bis-beta-carboline compound and medicinal salt thereof, preparation method and application | 中国人民解放军空军军医大学 | 2022-08-23 | — | — | CN | claimed |
| US-20080108115-A1 | ENHANCED PRODUCTION OF TAXOL AND TAXANES BY CELL CULTURES OF TAXUS SPECIES | DFB BIOTECH, INCORPORATED (US) | 2008-05-08 | — | — | US | claimed |
| US-7264951-B1 | Enhanced production of taxol and taxanes by cell cultures of Taxus species | PHYTON, INC. (US) | 2007-09-04 | — | — | US | claimed |
| CN-115974758-B | Carboxymethyl ketone compound and preparation method thereof | 生物岛实验室 | 2025-06-10 | — | — | CN | disclosed |
| CN-119332255-A | Electrochemical synthesis method of arundone derivatives | 云南师范大学 | 2025-01-21 | — | — | CN | disclosed |
| US-12053459-B2 | CDK2 inhibitors and methods of using the same | CEDILLA THERAPEUTICS, INC. (MA) | 2024-08-06 | — | — | US | disclosed |
| CN-118338898-A | Small molecule inhibitors of oncogenic CHD1L with preclinical anti-colorectal cancer activity | 科罗拉多州立大学董事会（法人团体） | 2024-07-12 | — | — | CN | disclosed |
| US-20240208998-A1 | COMPOUNDS FOR USE IN THE TREATMENT OF HYPERPROLIFERATIVE DISORDERS | UNIVERSITAT DE BARCELONA (ES) | 2024-06-27 | — | — | US | disclosed |
| CN-118086928-A | Method for electrochemical synthesis of pyrimidoindole derivative under mild condition | 湘潭大学 | 2024-05-28 | — | — | CN | disclosed |
| EP-1007523-A1 | INDOLE AND 2,3-DIHYDROINDOLE DERIVATIVES, THEIR PREPARATION AND USE | H. LUNDBECK A/S (DK) | 2000-06-14 | — | — | EP | disclosed |
| EP-0954596-A1 | ENHANCED PRODUCTION OF TAXANES BY CELL CULTURES OF $i(TAXUS) SPECIES | PHYTON, INC. (US) | 1999-11-10 | — | — | EP | disclosed |
| WO-1999005140-A1 | INDOLE AND 2,3-DIHYDROINDOLE DERIVATIVES, THEIR PREPARATION AND USE | H. LUNDBECK A/S (DK) | 1999-02-04 | — | — | WO | disclosed |
| WO-1997044476-A1 | ENHANCED PRODUCTION OF TAXANES BY CELL CULTURES OF TAXUS SPECIES | PHYTON, INC. (US) | 1997-11-27 | — | — | WO | disclosed |
| US-4147786-A | HYPOTENSIVE | CIBA-GEIGY CORPORATION (US) | 1979-04-03 | — | — | US | disclosed |
| US-4073911-A | ANTIHYPERTENSIVE AGENTS | CIBA-GEIGY CORPORATION (US) | 1978-02-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12053459-B2 | CDK2 inhibitors and methods of using the same | CDK2, CDK20, CDK2AP2 | GPR84 4585/4885ALDH1A1 3716/4885TSHR 3996/4885 |
| US-20240208998-A1 | COMPOUNDS FOR USE IN THE TREATMENT OF HYPERPROLIFERATIVE DISORDERS | VHL, PCNA, HRAS | GPR84 4531/4885ALDH1A1 1062/4885TSHR 4621/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.