Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 5/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | PHGDH | O43175 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ADA | P00813 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28775044 | 1.00 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2KMT2AMAPTMEN1 | |
| SCHEMBL4476068 | 0.85 | KMT2A (0.51) | ALDH1A1SMN1; SMN2KMT2AMAPTMEN1 | |
| SCHEMBL4476063 | 0.85 | KMT2A (0.51) | ALDH1A1SMN1; SMN2KMT2AMAPTMEN1 | |
| SCHEMBL838832 | 0.84 | KMT2A (0.51) | ALDH1A1SMN1; SMN2KMT2AMAPTMEN1 | |
| SCHEMBL840740 | 0.75 | KMT2A (0.43) | ALDH1A1SMN1; SMN2KMT2AMAPTMEN1 | |
| SCHEMBL840739 | 0.75 | KMT2A (0.43) | ALDH1A1SMN1; SMN2KMT2AMAPTMEN1 | |
| SCHEMBL8469055 | 0.73 | GAA (0.50) | ALDH1A1SMN1; SMN2KMT2AMAPTMEN1 | |
| SCHEMBL9423122 | 0.73 | MAOB (0.47) | ALDH1A1SMN1; SMN2KMT2AMAPTMEN1 | |
| SCHEMBL839050 | 0.70 | TACR1 (0.54) | ALDH1A1SMN1; SMN2KMT2AMAPTMEN1 | |
| SCHEMBL7905198 | 0.70 | GAA (0.44) | ALDH1A1SMN1; SMN2KMT2AMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8143052-B2 | Process for preparing optically active (S or R)-α amino acid and (R or S)-α amino acid ester in one phase organic reaction medium | UBE INDUSTRIES, LTD. (JP) | 2012-03-27 | — | — | US | disclosed |